催产素

大图：催產素的分子结构。小图：与神经垂体激素运载蛋白（neurophysin）结合的形状

催產素（英语：Oxytocin，又称缩宫素，简称为OT）是一種激素。可以在大腦裡自然產生, 有控制雌性哺乳動物乳汁分泌的作用。

1953年，科學家文森特·迪维尼奥成功發明了可應用到為婦女催生的人工合成催產素。1955年，迪维尼奥因此獲得諾貝爾化學奬。

由下視丘之視旁核製造，經下視丘腦下垂體路徑神經纖維送到後葉分泌。

合成、储存和释放

编辑

催产素，前多肽原
标识
代号	OXT; MGC126890; MGC126892; OT; OT-NPI
扩展标识	遗传学：167050 鼠基因：97453 同源基因：55494
基因本体论描述 分子功能 · hormone activity · neurohypophyseal hormone activity · protein binding · oxytocin receptor binding 细胞成分 · extracellular region · extracellular region · extracellular space · cytoplasm · stored secretory granule · terminal button 生物过程 · response to amphetamine · regulation of heart rate · maternal aggressive behavior · response to stress · signal transduction · elevation of cytosolic calcium ion concentration · heart development · female pregnancy · memory · grooming behavior · response to sucrose stimulus · positive regulation of norepinephrine secretion · response to organic cyclic compound · response to activity · sleep · positive regulation of prostaglandin secretion · response to estradiol stimulus · response to retinoic acid · response to progesterone stimulus · response to prostaglandin E stimulus · social behavior · response to cocaine · hyperosmotic salinity response · maternal behavior · sperm ejaculation · eating behavior · drinking behavior · response to peptide hormone stimulus · regulation of digestive system process · response to ether · negative regulation of blood pressure · positive regulation of blood pressure · positive regulation of ossification · positive regulation of female receptivity · positive regulation of synaptic transmission · response to glucocorticoid stimulus · response to cAMP · response to electrical stimulus · response to protein stimulus · regulation of sensory perception of pain · positive regulation of synaptogenesis · male mating behavior · positive regulation of penile erection · positive regulation of hindgut contraction · negative regulation of gastric acid secretion · positive regulation of uterine smooth muscle contraction
直系同源体
物种	人类	鼠类
Entrez	5020	18429
Ensembl	ENSG00000101405	ENSMUSG00000027301
UniProt	P01178	P35454
参考序列	NM_000915 (mRNA)	NM_011025.3 (mRNA)
	NP_000906（蛋白）	NP_035155.1（蛋白）
基因位置	染色体20: 3.05 - 3.05 Mb	染色体2: 130.4 - 130.4 Mb
PubMed查询	[1]	[2]

参见

• 活性多肽