副突变
维基百科，自由的百科全书
在表观遗传学中，副突变（英语：Paramutation，在台湾也称为類突變）是一个单位点的两个等位基因之间的互作，一个等位基因导致另一个等位基因发生遗传变化，乃是一種打破常規的遺傳模式。這種情況首先在玉米中發現，隨後在其他植物、真菌、甚至小鼠中發現[1]。而，用玉米所做的研究指出副突變是由RNA引導的[2]。
參考文獻 [编辑]
- BBC Science News - An easy to understand article involving paramutation
- Hollick JB, Dorweiler JE, Chandler VL. Paramutation and related allelic interactions (Review). Trends Genet. 1997.August, 13 (8): 302–8. doi:10.1016/S0168-9525(97)01184-0. PMID 9260515.
- Alleman M, Sidorenko L, McGinnis K, et al.. An RNA-dependent RNA polymerase is required for paramutation in maize. Nature. 2006.July, 442 (7100): 295–8. doi:10.1038/nature04884. PMID 16855589.
- Rassoulzadegan M, Grandjean V, Gounon P, Vincent S, Gillot I, Cuzin F. RNA-mediated non-mendelian inheritance of an epigenetic change in the mouse. Nature. 2006.May, 441 (7092): 469–74. doi:10.1038/nature04674. PMID 16724059.
- Chandler VL, Stam M. Chromatin conversations: mechanisms and implications of paramutation. Nat. Rev. Genet. (Review). 2004.July, 5 (7): 532–44. doi:10.1038/nrg1378. PMID 15211355.
- Stam M, Mittelsten Scheid O. Paramutation: an encounter leaving a lasting impression. Trends Plant Sci. 2005.June, 10 (6): 283–90. doi:10.1016/j.tplants.2005.04.009. PMID 15949762.
