岩沙海葵毒素

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岩沙海葵毒素
IUPAC名
(E,2S,3R,5R,8R,9S)-10-[(2R,3R,4R,5S,6R)-6-[(1S,2R,3S,4S,5R,11S)-12-[(1R,3S,5S,7R)-5-[(8S)-9-[(2R,3R,4R,5R,6S)-6-[(E,2S,3S,6S,9R,10R)-10-[(2S,4R,5S,6R)-6-[(2R,3R)-4-[(2R,3S,4R,5R,6S)-6-[(2S,3Z,5E,8R,9S,10R,12Z,17S,18R,19R,20R)-21-[(2R,3R,4R,5S,6R)-6-[(Z,3R,4R)-5-[(1S,3R,5R,7R)-7-[2-[(2R,3R,5S)-5-(aminomethyl)-3-hydroxy-tetrahydrofuran-2-yl]ethyl]-2,6-dioxabicyclo[3.2.1]octan-3-yl]-3,4-dihydroxy-pent-1-enyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,8,9,10,17,18,19-heptahydroxy-20-methyl-14-methylene-henicosa-3,5,12-trienyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,3-dihydroxy-butyl]-4,5-dihydroxy-tetrahydropyran-2-yl]-2,6,9,10-tetrahydroxy-3-methyl-dec-4-enyl]-3,4,5,6-tetrahydroxy-tetrahydropyran-2-yl]-8-hydroxy-nonyl]-1,3-dimethyl-6,8-dioxabicyclo[3.2.1]octan-7-yl]-1,2,3,4,5-pentahydroxy-11-methyl-dodecyl]-3,4,5-trihydroxy-tetrahydropyran-2-yl]-2,5,8,9-tetrahydroxy-N-[(E)-3-(3-hydroxypropylamino)-3-oxo-prop-1-enyl]-3,7-dimethyl-dec-6-enamide
识别
CAS号 77734-91-9
PubChem 11105289
ChemSpider 9280425
SMILES
InChI
InChIKey CWODDUGJZSCNGB-HQNRRURTBU
性质
化学式 C129H223N3O54
摩尔质量 2680.14 g·mol−1
危险性
主要危害 胸痛、哮喘样呼吸困难、心动过速、血压不稳、溶血。
若非注明,所有数据均出自一般条件(25 ℃,100 kPa)下。

岩沙海葵毒素[1]英语Palytoxin,又称沙群海葵毒素,或简称为海葵毒素)含有129个碳原子,64个手性中心。是一类从沙群海葵科岩沙海葵中提取的水溶性线性聚醚。作为一种毒素,其毒性主要表现为与钠钾泵结合以及抑制ATP合酶,有收缩血管以及升高血压作用。它的毒性在非蛋白质毒素中仅次于刺尾鱼毒素

参考文献[编辑]

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