甘油-3-磷酸脱氢酶 (NAD+)

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甘油-3-磷酸脱氢酶 (NAD+)
Glycerol-3-phosphate dehydrogenase 1.png
人源甘油-3-磷酸脱氢酶1(PDB 1x0v)
识别码
EC编号 1.1.1.8
CAS号 9075-65-4
数据库
IntEnz IntEnz浏览
BRENDA BRENDA入口
ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc 代谢路径
PRIAM 概述
PDB RCSB PDB PDBe PDBsum
基因本体 AmiGO / EGO

甘油-3-磷酸脱氢酶 (NAD+)英语glycerol-3-phosphate dehydrogenase (NAD+)EC 1.1.1.8)是一种以NAD+NADP+受体、作用于供体CH-OH基团上的氧化还原酶。这种催化以下酶促反应

sn-甘油-3-磷酸 + NAD+ \rightleftharpoons 磷酸甘油酮 + NADH + H+
Dihydroxyacetone phosphate to glycerol 3-phosphate en.svg

甘油-3-磷酸脱氢酶 (NAD+)主要参与甘油磷酸脂代谢过程。

参考文献[编辑]

  • Boyer, P.D., Lardy, H. and Myrback, K. (Eds.). The Enzymes 7 2nd. New York: Academic Press. 1963: 85–96. 
  • Brosemer RW, Kuhn RW. Comparative structural properties of honeybee and rabbit alpha-glycerophosphate dehydrogenases. Biochemistry. 1969, 8 (5): 2095–105. doi:10.1021/bi00833a047. PMID 4307630. 
  • O'Brien SJ, MacIntyre RJ. The -glycerophosphate cycle in Drosophila melanogaster. I Biochemical and developmental aspects. Biochem. Genet. 1972, 7 (2): 141–61. doi:10.1007/BF00486085. PMID 4340553. 
  • Warkentin DL, Fondy TP. Isolation and characterization of cytoplasmic L-glycerol-3-phosphate dehydrogenase from rabbit-renal-adipose tissue and its comparison with the skeletal-muscle enzyme. Eur. J. Biochem. 1973, 36 (1): 97–109. doi:10.1111/j.1432-1033.1973.tb02889.x. PMID 4200180. 
  • Albertyn J, van Tonder A, Prior BA. Purification and characterization of glycerol-3-phosphate dehydrogenase of Saccharomyces cerevisiae. FEBS. Lett. 1992, 308 (2): 130–2. doi:10.1016/0014-5793(92)81259-O. PMID 1499720. 
  • Koekemoer TC, Litthauer D, Oelofsen W. Isolation and characterization of adipose tissue glycerol-3-phosphate dehydrogenase. Int. J. Biochem. Cell. Biol. 1995, 27 (6): 625–32. doi:10.1016/1357-2725(95)00012-E. PMID 7671141.