线粒体16S RNA是一种存在于线粒体核糖体（mitoribosome，MR）39S核糖体亚基中的rRNA。[1][2]在人类细胞的线粒体中，该rRNA由MT-RNR2基因编码。MT-RNR2基因还同时编码了能抑制阿尔茨海默症相关基因表达的humanin。[3][4]
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参考文献 [编辑]
- ^ Noda R, Kim CG, Takenaka O, et al.. Mitochondrial 16S rRNA sequence diversity of hominoids. J. Hered. 2001, 92 (6): 490–6. doi:10.1093/jhered/92.6.490. PMID 11948216.
- ^ Nagy A, Wilhelm M, Kovacs G. Mutations of mtDNA in renal cell tumours arising in end-stage renal disease. J. Pathol. 2003.February, 199 (2): 237–42. doi:10.1002/path.1273. PMID 12533837.
- ^ Maximov V, Martynenko A, Hunsmann G, Tarantul V. Mitochondrial 16S rRNA gene encodes a functional peptide, a potential drug for Alzheimer's disease and target for cancer therapy. Med. Hypotheses. 2002.December, 59 (6): 670–3. doi:10.1016/S0306-9877(02)00223-2. PMID 12445508.
- ^ Tajima H, Niikura T, Hashimoto Y, et al.. Evidence for in vivo production of Humanin peptide, a neuroprotective factor against Alzheimer's disease-related insults. Neurosci. Lett. 2002.May, 324 (3): 227–31. doi:10.1016/S0304-3940(02)00199-4. PMID 12009529.
