细胞色素b5

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细胞色素b5
1jex cyto b5.png
结合了血红素的大鼠细胞色素b5
識別
符號 CYB5A
替換符號 CYB5
Entrez 1528
HUGO 2570
OMIM 250790
PDB 1JEX
RefSeq NM_001914
UniProt P00167
其他資料
基因座 18 q23
细胞色素b5
鉴定
标志 Cyt_B5
Pfam(蛋白家族查询站) PF00173
InterPro(蛋白数据整合站) IPR001199
PROSITE(蛋白数据站) PDOC00170

细胞色素b5[1]英语Cytochrome b5)是一种存在于动物植物真菌以及紫色光养菌中遍及的电子传递血红素蛋白。该细胞色素于微粒体线粒体中的变体是与膜相结合的,而细菌红细胞以及其他动物组织中的却是水溶性的。

参考文献[编辑]

  1. ^ [1]
  • Lederer, F. The cytochrome b5-fold: an adaptable module. Biochimie. 1994, 76 (7): 674–692. doi:10.1016/0300-9084(94)90144-9. PMID 7893819. 
  • Napier, J.A., Michaelson, L.V. and Sayanova, O. The role of cytochrome b5 fusion desaturases in the synthesis of polyunsaturated fatty acids. Prostaglandins, Leukotrienes and Essential Fatty Acids. 2003, 68 (2): 135–143. doi:10.1016/S0952-3278(02)00263-6. PMID 12538077. 
  • Rivera, M., Barillas-Mury, C., Christensen, K.A., Little, J.W., Wells, M.A. and Walker, F.A. Gene synthesis, bacterial expression, and 1H NMR spectroscopic studies of the rat outer mitochondrial membrane cytochrome b5. Biochemistry. 1992, 31 (48): 12233–12240. doi:10.1021/bi00163a037. PMID 1333795. 
  • Schenkman, J.B. and Jansson, I. The many roles of cytochrome b5. Pharmacol. Ther. 2003, 97 (2): 139–152. doi:10.1016/S0163-7258(02)00327-3. PMID 12559387. 

外部链接[编辑]

  • PDB 1B5A - Solution structure of rat cytochrome b5 (form A)
  • PDB 1B5B - Solution structure of rat cytochrome b5 (form B)
  • PDB 1CXY - X-ray structure of cytochrome b558 from Ectothiorhodospira vacuolata
  • OMIM 250790 - Methemoglobinemia due to deficiency of cytochrome b5