胃腸道基質腫瘤

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胃腸道基質腫瘤
分類系統及外部資源

部胃腸道基質腫瘤之組織病理影像(以蘇木精曙紅著色顯示)
DiseasesDB 33849
MeSH D046152
GIST內視鏡影像位於的底部,見於後屈(retroflexion)部
同樣的內視鏡前端GIST影像,顯示出腫瘤的高度凝塊

胃腸道基質腫瘤(Gastrointestinal stromal tumor,簡稱GIST)是一種腸道壁基質細胞病變,源由於身體的一個名為C-Kit(CD117)的基因出現突變,引致腸道壁的神經系統細胞演變成為腫瘤細胞。GIST的影響範圍不限定於腸道,而可以遍及食道小腸大腸直腸;而隨着GIST在消化道的不同部位發生,病者亦會出現不同的病徵[1]

註釋[编辑]

  1. ^ 朱建華,(2007年),〈腸話短說:認識胃腸道基質腫瘤〉,《都市日報》2007年11月23日號,P.34 健康。

參考文獻[编辑]

  1. De Silva MV, Reid R. Gastrointestinal stromal tumors (GIST): c-kit mutations, CD117 expression, differential diagnosis and targeted cancer therapy with imatinib. Pathol Oncol Res 2003;9:13-9. PMID 12704441.
  2. Kitamura Y, Hirota S, Nishida T. Gastrointestinal stromal tumors (GIST): a model for molecule-based diagnosis and treatment of solid tumors. Cancer Sci 2003:94:315-20. PMID 12824897.
  3. Miettinen M, Lasota J (2006). "Gastrointestinal stromal tumors: review on morphology, molecular pathology, prognosis, and differential diagnosis". Arch Pathol Lab Med 130 (10): 1466-78. PMID 17090188.

外部連結[编辑]

醫學研究連結[编辑]

病患導向之網站[编辑]

  • GIST Support International, An international organization for the support of GIST patients, families, and friends. Includes detailed information from some of the foremost experts on GIST, links to research, treatment options, GIST registry, adult and pediatric listservs, and affiliated GSI-Wiki.
  • Life Raft Group International GIST Advocacy Organization. Provides support to patients & families, through information, education, and innovative research.
  • GIST Info Patient links, includes information on new clinical trials and research
  • American Cancer Society Patient Guide to GIST tumors.
  • GIST 胃腸不可Blog