著名计算机科学家Edsger Dijkstra曾经指出：“计算机科学并不只是关于计算机，就像天文学并不只是关于望远镜一样。”（"Computer science is no more about computers than astronomy is about telescopes."）设计、部署计算机和计算机系统通常被认为是非计算机科学学科的领域。例如，研究计算机硬件被看作是计算机工程的一部分，而对于商业计算机系统的研究和部署被称为信息技术或者信息系统。然而，现如今也越来越多地融合了各类计算机相关学科的思想。计算机科学研究也经常与其它学科交叉，比如心理学，认知科学，语言学，数学，物理学，统计学和经济学。
^Denning, P. J.; Comer, D. E.; Gries, D.; Mulder, M. C.; Tucker, A.; Turner, A. J.; Young, P. R. Computing as a discipline. Communications of the ACM. 1989.Jan, 32: 9–23. doi:10.1145/63238.63239. volume = 64 编辑 "Computer science and engineering is the systematic study of algorithmic processes-their theory, analysis, design, efficiency, implementation, and application-that describe and transform information."
^Wegner, P.. Research paradigms in computer science. Proceedings of the 2nd international Conference on Software Engineering. San Francisco, California, United States: IEEE Computer Society Press, Los Alamitos, CA. October 13–15, 1976. "Computer science is the study of information structures"
^Abelson, H.; G.J. Sussman with J. Sussman. Structure and Interpretation of Computer Programs 2nd. MIT Press. 1996. ISBN0-262-01153-0. "The computer revolution is a revolution in the way we think and in the way we express what we think. The essence of this change is the emergence of what might best be called procedural epistemology — the study of the structure of knowledge from an imperative point of view, as opposed to the more declarative point of view taken by classical mathematical subjects."
^Parnas, D. L. Annals of Software Engineering. 1998, 6: 19–37. doi:10.1023/A:1018949113292.编辑, p. 19: "Rather than treat software engineering as a subfield of computer science, I treat it as an element of the set, Civil Engineering, Mechanical Engineering, Chemical Engineering, Electrical Engineering, [...]"
"Within more than 70 chapters, every one new or significantly revised, one can find any kind of information and references about computer science one can imagine. [...] all in all, there is absolute nothing about Computer Science that can not be found in the 2.5 kilogram-encyclopaedia with its 110 survey articles [...]." (Christoph Meinel, Zentralblatt MATH)
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Research evaluation for computer science, Informatics Europe report. Shorter journal version: Bertrand Meyer, Christine Choppy, Jan van Leeuwen and Jorgen Staunstrup, Research evaluation for computer science, in Communications of the ACM, vol. 52, no. 4, pp. 31-34, April 2009.