辅酶Q–细胞色素c还原酶

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泛醇—细胞色素c还原酶
Cytochrome1ntz.PNG
结合了泛醌的线粒体细胞色素bc1复合体晶体结构[1]
识别码
EC编号 1.10.2.2
CAS号 9027-03-6
数据库
IntEnz IntEnz浏览
BRENDA BRENDA入口
ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc 代谢路径
PRIAM 概述
PDB RCSB PDB PDBe PDBsum
基因本体 AmiGO / EGO

泛醇—细胞色素c还原酶英语Ubiquinol—cytochrome-c reductaseEC 1.10.2.2)在酶学中是指一种催化如下化学反应的酶:

QH2 + 2 高铁细胞色素c \rightleftharpoons Q + 2 亚铁细胞色素c + 2 H+

因此,此酶的两个底物分别是二氢醌(QH2)与高铁(Fe3+细胞色素c,而其三个产物则分别是(Q)、亚铁(Fe2+)细胞色素c以及氢离子

参考文献[编辑]

  1. ^ PDB 1ntz; Gao X, Wen X, Esser L, Quinn B, Yu L, Yu CA, Xia D. Structural basis for the quinone reduction in the bc1 complex: a comparative analysis of crystal structures of mitochondrial cytochrome bc1 with bound substrate and inhibitors at the Qi site. Biochemistry. 2003.August, 42 (30): 9067–80. doi:10.1021/bi0341814. PMID 12885240. 

深入阅读[编辑]

  • Marres CM, Slater EC. Polypeptide composition of purified QH2:cytochrome c oxidoreductase from beef-heart mitochondria. Biochim. Biophys. Acta. 1977, 462 (3): 531–548. doi:10.1016/0005-2728(77)90099-8. PMID 597492. 
  • Rieske JS. Composition, structure, and function of complex III of the respiratory chain. Biochim. Biophys. Acta. 1976, 456 (2): 195–247. PMID 788795. 
  • Wikstrom M, Krab K, Saraste M. Proton-translocating cytochrome complexes. Annu. Rev. Biochem. 1981, 50: 623–655. doi:10.1146/annurev.bi.50.070181.003203. PMID 6267990. 

外部链接[编辑]