金胺O

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Auramine O
IUPAC名
bis[4-(dimethylamino)phenyl]methaniminium chloride
别名 Basic yellow 2, Pyocatanium aureum, aizen auramine, Pyoktanin Yellow, Canary Yellow, Pyoktanin, or C.I. 41000
识别
CAS号 2465-27-2
PubChem 17170
ChemSpider 16254
SMILES
InChI
InChIKey JPIYZTWMUGTEHX-UHFFFAOYAY
性质
化学式 C17H22ClN3
摩尔质量 303.83 g·mol−1
熔点 267 °C
危险性
警示术语 R:R22 R24 R40
安全术语 S:S36/37 S45
若非注明,所有数据均出自一般条件(25 ℃,100 kPa)下。

金胺O是一種二芳基甲烷螢光染料,常態下為黃色針狀結晶。極易溶於水,易溶於乙醇

金胺O可用於抗酸細菌(例如Mycobacterium), 其方法類似抗酸染色法[1] 也被當做希夫試劑的螢光版來使用。[2]

金胺-若丹明染色法中與若丹明B一起用來給結核桿菌染色。[3][4] 同時也可用作防腐劑

參考文獻[编辑]

  1. ^ Kommareddi S, Abramowsky C, Swinehart G, Hrabak L. Nontuberculous mycobacterial infections: comparison of the fluorescent auramine-O and Ziehl-Neelsen techniques in tissue diagnosis. Hum Pathol. 1984, 15 (11): 1085–9. doi:10.1016/S0046-8177(84)80253-1. PMID 6208117. 
  2. ^ Khavkin T, Kudryavtseva M, Dragunskaya E, Polotsky Y, Kudryavtsev B. Fluorescent PAS-reaction study of the epithelium of normal rabbit ileum and after challenge with enterotoxigenic Escherichia coli. Gastroenterology. 1980, 78 (4): 782–90. PMID 6986320. 
  3. ^ Truant J, Brett W, Thomas W. Fluorescence microscopy of tubercle bacilli stained with auramine and rhodamine. Henry Ford Hosp Med Bull. 1962, 10: 287–96. PMID 13922644. 
  4. ^ Arrowood M, Sterling C. Comparison of conventional staining methods and monoclonal antibody-based methods for Cryptosporidium oocyst detection. J Clin Microbiol. 1989, 27 (7): 1490–5. PMC 267601. PMID 2475523. 

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