piRNA

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piRNA全名Piwi-interacting RNA,是一類小型RNA分子,長度大約是29到30個核苷酸。在许多动物(包括无脊椎动物)的生殖腺中都有被发现,並且可以和Piwi蛋白結合形成piRNA複合物(piRNA complexes,piRCs)。與RNA沉默(RNA silencing)作用有關。

相關文獻[编辑]

  • N.C. Lau et al., "Characterization of the piRNA Complex from Rat Testes," Science 313, 363 (2006)
  • V.N. Kim, "Small RNAs Just Got Bigger: Piwi-Interacting RNAs (piRNAs) in Mammalian Testes," Genes Dev. 20, 1993 (2006)
  • A. Girard et al., "A Germline-Specific Class of Small RNAs Binds Mammalian Piwi Proteins," Nature 442, 199 (2006)
  • A. Aravin et al., "A Novel Class of Small RNAs Bind to MILI Protein in Mouse Testes," Nature 442, 203 (2006)
  • S.T. Grivna et al., "A Novel Class of Small RNAs in Mouse Spermatogenic Cells," Genes Dev. 20, 1709 (2006)