SNAPC4
| 小核RNA激活蛋白复合体，多肽4，190千道尔顿 Small nuclear RNA activating complex, polypeptide 4, 190kDa | |||
|---|---|---|---|
| 标识 | |||
| 代号 | SNAPC4; PTFalpha; SNAP190 | ||
| 扩展标识 | 遗传学：602777 鼠基因：2443935 同源基因：2321 GeneCards: SNAPC4 Gene | ||
| RNA表达模式 | |||
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| 更多表达数据 | |||
| 直系同源体 | |||
| 物种 | 人类 | 小鼠 | |
| Entrez | 6621 | 227644 | |
| Ensembl | ENSG00000165684 | ENSMUSG00000036281 | |
| UniProt | Q5SXM2 | Q8BP86 | |
| mRNA序列 | NM_003086 | NM_172339 | |
| 蛋白序列 | NP_003077 | NP_758842 | |
| 基因位置 |
Chr 9: 139.27 – 139.29 Mb |
Chr 2: 26.36 – 26.38 Mb | |
| PubMed查询 | [1] | [2] | |
snRNA激活蛋白复合体第四亚基（英語：snRNA-activating protein complex subunit 4）是一个由人类基因 SNAPC4 编码的蛋白质[1][2]。
相互作用[编辑]
SNAPC4能与SNAPC1[3]、POU2F1[1][4]和SNAPC2[1][3]相互作用。
参考文献[编辑]
- ^ 1.0 1.1 1.2 Wong MW, Henry RW, Ma B, Kobayashi R, Klages N, Matthias P, Strubin M, Hernandez N. The Large Subunit of Basal Transcription Factor SNAPc Is a Myb Domain Protein That Interacts with Oct-1. Mol Cell Biol. January 1998, 18 (1): 368–77. PMC 121507
. PMID 9418884. 引证错误：带有name属性“pmid9418884”的<ref>标签用不同内容定义了多次 - ^ Entrez Gene: SNAPC4 small nuclear RNA activating complex, polypeptide 4, 190kDa.
- ^ 3.0 3.1 Ma, B; Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. (United States). February 2001, 276 (7): 5027–35. ISSN 0021-9258. PMID 11056176. doi:10.1074/jbc.M009301200.
- ^ Hovde, Stacy; Brooks Aimee, Strong Katie, Geiger James H. Crystallization of the Oct-1/SNAP190 peptide/DNA complex. Acta Crystallogr. D Biol. Crystallogr. (Denmark). March 2002, 58 (Pt 3): 511–2. ISSN 0907-4449. PMID 11856838. doi:10.1107/S0907444901021461.
延伸阅读[编辑]
- Henry RW, Sadowski CL, Kobayashi R, Hernandez N. A TBP-TAF complex required for transcription of human snRNA genes by RNA polymerase II and III. Nature. 1995, 374 (6523): 653–6. PMID 7715707. doi:10.1038/374653a0.
- Ma B, Hernandez N. A map of protein-protein contacts within the small nuclear RNA-activating protein complex SNAPc. J. Biol. Chem. 2001, 276 (7): 5027–35. PMID 11056176. doi:10.1074/jbc.M009301200.
- Hovde S, Brooks A, Strong K, Geiger JH. Crystallization of the Oct-1/SNAP190 peptide/DNA complex. Acta Crystallogr. D Biol. Crystallogr. 2002, 58 (Pt 3): 511–2. PMID 11856838. doi:10.1107/S0907444901021461.
- Strausberg RL; Feingold EA; Grouse LH; et al. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Proc. Natl. Acad. Sci. U.S.A. 2003, 99 (26): 16899–903. PMC 139241 . PMID 12477932. doi:10.1073/pnas.242603899. 已忽略未知参数
|author-separator=(帮助) - Hinkley CS; Hirsch HA; Gu L; et al. The small nuclear RNA-activating protein 190 Myb DNA binding domain stimulates TATA box-binding protein-TATA box recognition. J. Biol. Chem. 2003, 278 (20): 18649–57. PMID 12621023. doi:10.1074/jbc.M204247200. 已忽略未知参数
|author-separator=(帮助) - Ota T; Suzuki Y; Nishikawa T; et al. Complete sequencing and characterization of 21,243 full-length human cDNAs. Nat. Genet. 2004, 36 (1): 40–5. PMID 14702039. doi:10.1038/ng1285. 已忽略未知参数
|author-separator=(帮助) - Humphray SJ; Oliver K; Hunt AR; et al. DNA sequence and analysis of human chromosome 9. Nature. 2004, 429 (6990): 369–74. PMC 2734081 . PMID 15164053. doi:10.1038/nature02465. 已忽略未知参数
|author-separator=(帮助) - Beausoleil SA; Jedrychowski M; Schwartz D; et al. Large-scale characterization of HeLa cell nuclear phosphoproteins. Proc. Natl. Acad. Sci. U.S.A. 2004, 101 (33): 12130–5. PMC 514446 . PMID 15302935. doi:10.1073/pnas.0404720101. 已忽略未知参数
|author-separator=(帮助) - Gu L, Esselman WJ, Henry RW. Cooperation between small nuclear RNA-activating protein complex (SNAPC) and TATA-box-binding protein antagonizes protein kinase CK2 inhibition of DNA binding by SNAPC. J. Biol. Chem. 2005, 280 (30): 27697–704. PMID 15955816. doi:10.1074/jbc.M503206200.
- Gu L, Husain-Ponnampalam R, Hoffmann-Benning S, Henry RW. The protein kinase CK2 phosphorylates SNAP190 to negatively regulate SNAPC DNA binding and human U6 transcription by RNA polymerase III. J. Biol. Chem. 2007, 282 (38): 27887–96. PMID 17670747. doi:10.1074/jbc.M702269200.