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Β1肾上腺素受体激动药

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β1肾上腺素受体刺激劑(Beta1-adrenergic agonists)又名為 β1肾上腺素受体激动剂,是一種能選擇性作用於β1肾上腺素受体英语beta-1 adrenergic receptor激动剂,β1肾上腺素受体刺激劑主要作用於心臟,通常由正腎上腺素激活。正腎上腺素則主要由交感神經的腎上腺素和循環全身的腎上腺素釋放而得。β1肾上腺素受体刺激劑激活後的效果主要為刺激心臟,例如:加速心率心肌收縮能力英语myocardial contractility心導速率英语conduction velocity[1]

地诺帕明英语denopamine[2][3]多保他命扎莫特羅英语xamoterol都屬於β1肾上腺素受体刺激劑。

文獻[编辑]

  1. ^ Sakuma, Tsutomu; Hida, Mieko; Nambu, Yoshihiro; Osanai, Kazuhiro; Toga, Hirohisa; Takahashi, Keiji; Ohya, Nobuo; Inoue, Masao; Watanabe, Yoh. Beta1-Adrenergic Agonist Is a Potent Stimulator of Alveolar Fluid Clearance in Hyperoxic Rat Lungs.. The Japanese Journal of Pharmacology (Japanese Pharmacological Society). 2001, 85 (2): 161–166. ISSN 0021-5198. doi:10.1254/jjp.85.161. 
  2. ^ Sakuma T, Hida M, Nambu Y, 等. Beta1-adrenergic agonist is a potent stimulator of alveolar fluid clearance in hyperoxic rat lungs. Jpn. J. Pharmacol. February 2001, 85 (2): 161–6. PMID 11286398. doi:10.1254/jjp.85.161. 
  3. ^ Nishio R, Matsumori A, Shioi T, 等. Denopamine, a beta1-adrenergic agonist, prolongs survival in a murine model of congestive heart failure induced by viral myocarditis: suppression of tumor necrosis factor-alpha production in the heart. J. Am. Coll. Cardiol. September 1998, 32 (3): 808–15. PMID 9741531. doi:10.1016/S0735-1097(98)00314-3.