- 1925年: 弗朗西斯·斯科特·基·菲茨杰拉德 《了不起的蓋茨比》
- 1936年: 威廉·福克納 《押沙龍，押沙龍！》
- 1938年: 約翰·多斯·帕索斯 《美國》
- 1939年: 約翰·史坦貝克 《憤怒的葡萄》
- 1951年: 杰罗姆·大卫·塞林格《麥田捕手》
- 1952年: 拉尔夫·艾里森 《隱形人》 Invisible Man 
- 1953年: 索尔·贝娄《阿奇正傳》（The Adventures of Augie March）
- 1955年: 弗拉基米爾·納博可夫《羅莉塔》
- 1960年: 哈波·李《梅崗城故事》
- 1973年: 托马斯·品钦 《萬有引力之虹》
- 1975年: 威廉·蓋迪斯（William Gaddis） 《J R》
- 1985年: 戈馬克·麥卡錫 《血色子午線》（Blood Meridian）
- 1987年: 托妮·莫里森 《寵兒》（Beloved）
- 1997年: 托马斯·品钦 《梅森和迪克逊》（Mason & Dixon）
- Buell, Lawrence. The Unkillable Dream of the Great American Novel: Moby-Dick as Test Case. [2010-10-26]. American Literary History Volume 20, Issue 1-2 Pp. 132-155.
- Brown, Robert B. One Hundred Years of Huck Finn. American Heritage Publishing. June/July 1984 [2011-12-10]. It was called the “great American novel” as early as 1891 by the English writer Andrew Lang... ”
- The Columbia History of the American Novel By Emory Elliott, Cathy N. Davidson p. 323 "The Great Gatsby (1925), a work still frequently nominated as 'the great American novel.'"
- Hirsch, Arthur. The real great American Novel: 'Absalom, Absalom!' Faulkner: His ninth novel, for its span, its revelation, its American essence, stands above all others in reaching for this literary absolute.. The Baltimore Sun (Baltimore, MD). 1997-11-16 [2010-09-21].
- Hammond, Margo. Norman Mailer on the Media and the Message. Book Babes. The Poynter Institute. February 6, 2004 [2010-09-21]. Norman Mailer is a Pulitzer Prize winning literary critic, and it is his opinion that: "The Great American Novel is no longer writable. We can't do what John Dos Passos did. His trilogy on America came as close to the Great American Novel as anyone. You can't cover all of America now. It's too detailed."
- Dana, Gioia. The Grapes of Wrath Radio Show - Transcript. The Big Read. The National Endowment for the Arts. [2010-09-22]. Richard Rodriguez is a famous American writer. In this interview he referred to the Grapes of Wrath as The Great American Novel: "There hasn't been anything like this novel since it was written. And this is the great American novel that everyone keeps waiting for but it has been written now."
- Nixon, Rob. The Grapes of Wrath. This Month Spotlight. Turner Classic Movies. [2010-09-22]. Nixon quotes John Springer, author of The Fondas (Citadel, 1973), a book about Henry Fonda and his role in film version of The Grapes of Wrath: "The Great American Novel made one of the few enduring Great American Motion Pictures."
- Wolverton, II, Joe. J.D. Salinger, Dead at 91. The New American Magazine. January 29, 2010 [2010-09-22]. "While a student at Ursinus College in Collegeville, Pennsylvania, Salinger amused and annoyed his fellow students by traipsing about campus proclaiming that he would be the author of the next Great American Novel. That his Catcher in the Rye was such a book is indisputable.
- Giles, Patrick, The Great American Novel, Los Angeles Times, 2002-09-15
- Amis, Martin, Review, The Atlantic Monthly (quoted by Powell's Books) Martin Amis is a well-known British novelist and professor of creative writing at the University of Manchester. It is his opinion that "The Adventures of Augie March is the Great American Novel. Search no further. All the trails went cold 42 years ago. The quest did what quests very rarely do; it ended."
- Williams, Mary Elizabeth. Lolita by Vladimir Nabokov. Personal Best. Salon. [2010-09-22]. Mary Elizabeth Williams is Salon's Table Talk host. She opens her review with these lines: "Some say the Great American Novel is Huckleberry Finn, some say it's The Jungle, some say it's The Great Gatsby. -- Vladimir Nabokov's Lolita".
- Jameson, Frederick. The Seeds of Time. New York, NY: Columbia University Press. 1996: 214 pages. "These are familiar features of daily life in the super state from which, it should be noted, high modernism in the United States - in theory and in practice alike, fifties aestheticism organized around Pound and Henry James and Wallace Stevens and the New Criticism - was in desperate flight; of our great modern writers, only Nabokov handled this kind of material, in Lolita, which thereby at once became The Great American Novel,- but of course he was a foreigner to begin with." (Page 146-147).
- Puente, Maria. 'To Kill a Mockingbird': Endearing, enduring at 50 years. USA Today. 2010-07-08. "It is Lee's only book and one of the handful that could earn the title of Great American Novel."
- Ruch, Alan. Introduction to GR. The Modern World. April 1, 1997 [2010-09-22]. "It is the Great American Novel come at last, a postmodern masterpiece."
- Weisenburger, Steven. A Gravity's Rainbow Companion. University of Georgia Press. 2006: 412. "Thomas Pynchon's big book quickly confirmed him as one of the few novelists of unprecedented genius to emerge in the postwar era. Here was the Great American Novel at last. The reviewers' favorite comparisons were to Moby Dick and Ulysses."
- San Francisco Review of Books. "Gaddis has written the long-awaited great American novel... A beautiful book and a brilliant author."
- What Is the Best Work of American Fiction of the Last 25 Years?
- Morton, Brian. Scotland on Sunday. "Pynchon's finest work yet...if anyone is still looking for the Great American Novel then this may well be it."
- Benjamin Alsup. Jonathan Franzen Will Go Down Swinging - Some people believe the era of the Great American Novel is over. Freedom makes them look like fools.. August 11, 2010 [2014-12-13] （英语）.
- Brown, Herbert R. "The Great American Novel." American Literature 7.1 (1935): 1–14.
- Knox, George. "The Great American Novel: Final Chapter." American Quarterly 21.4 (1969): 667–682.