全氟癸酸

全氟癸酸
	IUPAC名; 2,2,3,3,4,4,5,5,6,6,7,7,8,8,9,9,10,10,10-nonadecafluorodecanoic acid
识别
CAS号	335-76-2
PubChem	9555
ChemSpider	9181
SMILES	C(=O)(C(C(C(C(C(C(C(C(C(F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)(F)F)O;
InChI	1S/C10HF19O2/c11-2(12,1(30)31)3(13,14)4(15,16)5(17,18)6(19,20)7(21,22)8(23,24)9(25,26)10(27,28)29/h(H,30,31);
InChIKey	PCIUEQPBYFRTEM-UHFFFAOYSA-N
Gmelin	35659
性质
化学式	C10HF19O2
摩尔质量	514.08 g·mol−1
熔点	77-81 °C（269 K）
沸点	218 °C（491 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

全氟癸酸（英語：Perfluorodecanoic acid，缩写PFDA）是一种全氟羧酸表面活性剂^[1]，工业上常用于湿润剂和阻燃劑^[2]。和其它含氟表面活性剂类似，PFDA的使用也引发了健康问题^[3]，限制了其使用^[4]。 PFDA也可以作为研究过氧化物酶体增殖的化学探针^[5]^[6]。

参考文献[编辑]

^ Reich, Ieva L.; Reich, Hans J.; Menahan, Lawrence A.; Peterson, Richard E. Synthesis of 14C-labeled perfluorooctanoic and perfluorodecanoic acids; purification of perfluorodecanoic acid. Journal of Labelled Compounds and Radiopharmaceuticals. October 1987, 24 (10): 1235–1244. doi:10.1002/jlcr.2580241011.
^ Harris, M. Developmental toxicity of perfluorodecanoic acid in C57BL/6N mice. Fundamental and Applied Toxicology. April 1989, 12 (3): 442–448. doi:10.1016/0272-0590(89)90018-3 （英语）.
^ Danish study links perfluorinated chemicals to miscarriage. Chemical Watch. [25 March 2019] （英语）.
^ Germany and Sweden propose restrictions on six PFASs. Chemical Watch. 14 May 2015 [25 March 2019]. （原始内容存档于2022-01-19）（英语）.
^ Vanden Heuvel, John P. Perfluorodecanoic acid as a useful pharmacologic tool for the study of peroxisome proliferation. General Pharmacology: The Vascular System. October 1996, 27 (7): 1123–1129. doi:10.1016/0306-3623(95)00126-3.
^ Chen, Li-Chuan; Tatum, Vickie; Glauert, Howard P.; Chow, Ching K. Peroxisome proliferator perfluorodecanoic acid alters glutathione and related enzymes. Journal of Biochemical and Molecular Toxicology. 2001, 15 (2): 107–113. ISSN 1095-6670. doi:10.1002/jbt.6 （英语）.