埃勒斯-當洛二氏症候群
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埃勒斯-當洛二氏症候群 Ehlers–Danlos syndromes |
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Individual with EDS displaying skin hyperelasticity | |
醫學專科 | Medical genetics |
症状 | Overly flexible joints, stretchy skin, abnormal scar formation[1] |
併發症 | Aortic dissection, joint dislocations, osteoarthritis[1] |
常見始發於 | Birth or early childhood[2] |
病程 | Long term[3] |
肇因 | Genetic[1] |
診斷方法 | Genetic testing, skin biopsy[3] |
相似疾病或共病 | Marfan syndrome, cutis laxa syndrome, familial joint hypermobility syndrome[3] |
治療 | Supportive[4] |
預後 | Depends on the type[3] |
盛行率 | 1 in 5,000[1] |
埃勒斯-當洛二氏症候群(英语:Ehlers-Danlos Syndrome,縮寫為 EDS),又稱皮膚彈力過度症(英语:Cutis hyperelastica)、鬆皮症、先天性結締組織異常症候群,是一種遺傳疾病,因膠原蛋白(第一型或第三型)生成的缺陷,造成結締組織異常而產生。特徵是會使得病人身上部份肌肉與關節組織,逐漸變得異常柔軟、有彈性,之後漸漸鬆弛。
這個病症首先由丹麥醫師愛德華·埃勒斯(Edvard Ehlers)與法國醫師昂利-亞歷山大·當洛(Henri-Alexandre Danlos),在二十世紀初時所確認,因此而命名。
症狀分類[编辑]
在過去,埃勒斯-當洛二氏症候群被分成十種類型。在1997年,研究人員提出了一個比較簡單的分類方式,將它的主要類型分成六種。
註釋[编辑]
- ^ 1.0 1.1 1.2 1.3 Ehlers–Danlos syndrome. Genetics Home Reference. [8 May 2016]. (原始内容存档于8 May 2016).
- ^ Anderson, Bryan E. The Netter Collection of Medical Illustrations - Integumentary System E-Book 2. Elsevier Health Sciences. 2012: 235. ISBN 1455726648. (原始内容存档于2017-11-05) (英语).
- ^ 3.0 3.1 3.2 3.3 Lawrence, Elizabeth J. (2005). "The clinical presentation of Ehlers–Danlos syndrome". Advances in Neonatal Care. 5 (6): 301–14. doi:10.1016/j.adnc.2005.09.006. PMID 16338669.
- ^ Ferri, Fred F. Ferri's Netter Patient Advisor. Elsevier Health Sciences. 2016: 939. ISBN 9780323393249. (原始内容存档于2017-11-05) (英语).
外部連結[编辑]
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维基共享资源中相关的多媒体资源:埃勒斯-當洛二氏症候群 |
- 开放式目录计划中和埃勒斯-當洛二氏症候群相关的内容
- Ehlers–Danlos Syndrome, Classic Type. Includes: Ehlers–Danlos Syndrome Type I, Ehlers–Danlos Syndrome Type II
- University of Washington Medicine, Orthopaedics and Sports Medicine Multi-page explanation of EDS, including symptoms, genetics, diagnosis, and treatment
- National Institute of Health on Hypermobility EDS
- GeneReviews/NCBI/NIH/UW entry on Ehlers–Danlos Syndrome Type IV
- eds at NIH/UW GeneTests
- Ehlers–Danlos National Foundation
- Hypermobile – A blog about Ehlers Danlos Syndrome The lack of clinical distinction between the hypermobility type of Ehlers–Danlos syndrome and the joint hypermobility syndrome (a.k.a. hypermobility syndrome)
- Management of pain and fatigue in the joint hypermobility syndrome (a.k.a. Ehlers–Danlos syndrome, hypermobility type): principles and proposal for a multidisciplinary approach
- Anesthesia for EDS patients - Guidelines at orphananesthesia.eu
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Template:Collagen disease Template:Posttranslational modification disorders Template:Congenital malformations and deformations of integument