抗高血压药

维基百科,自由的百科全书
跳转至: 导航搜索

抗高血壓藥(英文:Anti-hypertensives

作用机理[编辑]

此类药直接作用于小动脉平滑肌,使血管扩张血压降低,其机理可能是干预了血管平滑肌细胞的钙离子内流或胞内储存钙离子的释放。[來源請求]

代表药物[编辑]

肼屈嗪
米诺地尔
硝普钠

参见[编辑]

參考文獻[编辑]

  • Chobanian AV et al.(2003)"The Seventh Report of the Joint National Committee on Prevention, Detection, Evaluation, and Treatment of High Blood Pressure: the JNC 7 report." JAMA. 289,2560-72. PMID 12748199
  • ALLHAT Officers and Coordinators for the ALLHAT Collaborative Research Group(2002)"Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT)." JAMA. 288,2981-97. PMID 12479763
  • Bangalore S, Kamalakkannan G, Parkar S and Messerli FH.(2007)"Fixed-dose combinations improve medication compliance: a meta-analysis."Am.J.Med. 120, 713-9. PMID 17679131