肌肉减少症

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肌肉减少症(英語:Sarcopenia)又称肌少症,是指骨骼肌在质量(mass)、品质(quality)和强度(strength)上随着年龄或不活动产生退化性损失。此术语的英文是来自希臘語σάρξ(肉体)和πενία(贫乏)。肌肉减少症是老化或退化过程,50岁以后每年有0.5-1%的损失。可以通过病理和行为因素如营养不足加速。肌少症是衰弱症英语frailty syndrome的一个構成要素[1]

肌少症的诊断标准有许多要件,临床上特别关注四肢骨骼肌质量(appendicular skeletal muscle mass,ASM)[2],以其指数 ASMI(ASM/身高2)为诊断肌少症的要件之一,若个体骨骼肌质量低于健康成人平均值两个标准差以上,则要件成立;以亚洲人种来说,即男性 ASMI <7.0 kg/m2,女性 <5.4 kg/m2[3]

參考資料[编辑]

  1. ^ Peterson SJ, Mozer M. Differentiating Sarcopenia and Cachexia Among Patients With Cancer. Nutrition in Clinical Practice. February 2017, 32 (1): 30–39. PMID 28124947. doi:10.1177/0884533616680354. 
  2. ^ Han, Yanxia MMa; Wu, Zhenyun MMa; Chen, Yi MMa; Kan, Yanan MMb; Geng, Min MMb; Xu, Nuo MMb; Qian, Hongying MBa; Wang, Hai Fang MMa; Niu, Meie MMa,∗ Factors associated with appendicular skeletal muscle mass among male Chinese patients with stable chronic obstructive pulmonary disease, Medicine: October 2019 - Volume 98 - Issue 40 - p e17361 doi: 10.1097/MD.0000000000017361
  3. ^ Chen LK, Woo J, Assantachai P, Auyeung TW, Chou MY, Iijima K, Jang HC, Kang L, Kim M, Kim S, Kojima T, Kuzuya M, Lee JSW, Lee SY, Lee WJ, Lee Y, Liang CK, Lim JY, Lim WS, Peng LN, Sugimoto K, Tanaka T, Won CW, Yamada M, Zhang T, Akishita M, Arai H. Asian Working Group for Sarcopenia: 2019 Consensus Update on Sarcopenia Diagnosis and Treatment. J Am Med Dir Assoc. 2020 Mar;21(3):300-307.e2. doi: 10.1016/j.jamda.2019.12.012. Epub 2020 Feb 4. PMID 32033882.

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