骨质软化

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骨质软化
Calcitriol.svg
胆钙化醇(维生素D3)的缺乏是引起骨质软化最常见的原因
类型bone remodeling disease[*]
分类和外部资源
醫學專科風濕病學
ICD-10M83
ICD-9-CM268.2
DiseasesDB9351
MedlinePlus000376
eMedicine985510412862
Patient UK英语Patient UKvitamin-d-deficiency-including-osteomalacia-and-rickets 骨质软化

骨质软化又稱軟骨病,是一种因骨骼代谢障碍而引起的骨骼软化疾病,引起骨骼代谢英语Bone remodeling障碍的原因有人體缺乏磷酸盐维生素D抑或是鈣的吸收不足。儿童要是出現骨质疏松則称为佝僂病,正因为如此,骨质疏松症这一稱呼常常用于程度较轻的成人患者。骨质软化的症状和体征有身體出現弥漫性疼痛、肌肉无力和脆弱的骨骼[1][2][3][4][5]。及時补充维生素D和钙可以预防和治疗骨质软化[6]

参考文献[编辑]

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  3. ^ Barros, NM; Hoac, B; Neves, RL; Addison, WN; Assis, DM; Murshed, M; Carmona, AK; McKee, MD. Proteolytic processing of osteopontin by PHEX and accumulation of osteopontin fragments in Hyp mouse bone, the murine model of X-linked hypophosphatemia.. Journal of Bone and Mineral Research. March 2013, 28 (3): 688–99. PMID 22991293. doi:10.1002/jbmr.1766.  无效|subscription=free (帮助)
  4. ^ McKee, MD; Hoac, B; Addison, WN; Barros, NM; Millán, JL; Chaussain, C. Extracellular matrix mineralization in periodontal tissues: Noncollagenous matrix proteins, enzymes, and relationship to hypophosphatasia and X-linked hypophosphatemia.. Periodontology 2000. October 2013, 63 (1): 102–22. PMC 3766584可免费查阅. PMID 23931057. doi:10.1111/prd.12029. 
  5. ^ Boukpessi, T; Gaucher, C; Léger, T; Salmon, B; Le Faouder, J; Willig, C; Rowe, PS; Garabédian, M; Meilhac, O. Abnormal presence of the matrix extracellular phosphoglycoprotein-derived acidic serine- and aspartate-rich motif peptide in human hypophosphatemic dentin.. The American Journal of Pathology. August 2010, 177 (2): 803–12. PMC 2913338可免费查阅. PMID 20581062. doi:10.2353/ajpath.2010.091231. 
  6. ^ Longo, Dan L.; 等. Harrison's principles of internal medicine. 18th. New York: McGraw-Hill. 2012. ISBN 978-0-07174889-6.