SH3结构域

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SH3 domain
1shg SH3 domain.png
α-血影蛋白的SH3结构域的飘带图,PDB代码1SHG,N-端为蓝色,C-端为红色
鑑定
標誌SH3_1
PfamPF00018
Pfam宗系CL0010
InterPro英语InterProIPR001452
SMART英语Simple Modular Architecture Research ToolSM00326
PROSITE英语PROSITEPS50002
 SCOP英语Structural Classification of Proteins1shf / SUPFAM
CDD英语Conserved Domain Databasecd00174


SH3结构域(英語:SH3 domain,全称Src同源3结构域,英語:SRC Homology 3 Domain)是最早在病毒接头蛋白v-Crk及酪氨酸激酶SrcAbl中发现的长约60个氨基酸残基的保守结构域[1][2],在磷酸肌醇3-激酶Ras超家族G蛋白cdc25中也存在[3][4][5]

参考文献[编辑]

  1. ^ Pawson T, Schlessingert J. SH2 and SH3 domains. Current Biology. July 1993, 3 (7): 434–42. PMID 15335710. doi:10.1016/0960-9822(93)90350-W. 
  2. ^ Mayer BJ. SH3 domains: complexity in moderation. Journal of Cell Science. April 2001, 114 (Pt 7): 1253–63. PMID 11256992. doi:  请检查|doi=值 (帮助). 
  3. ^ Musacchio A, Gibson T, Lehto VP, Saraste M. SH3--an abundant protein domain in search of a function. FEBS Letters. July 1992, 307 (1): 55–61. PMID 1639195. doi:10.1016/0014-5793(92)80901-R. 
  4. ^ Mayer BJ, Baltimore D. Signalling through SH2 and SH3 domains. Trends in Cell Biology. January 1993, 3 (1): 8–13. PMID 14731533. doi:10.1016/0962-8924(93)90194-6. 
  5. ^ Pawson T. Protein modules and signalling networks. Nature. February 1995, 373 (6515): 573–80. PMID 7531822. doi:10.1038/373573a0. 

外部链接[编辑]