物質濫用症候群（Substance Abused Disorder or Substance Use Disorder） 青少年與成人注意力不足過動症患者皆有相較對照組較高的物質濫用風險。物質濫用的原因之一可能是腦中原有的回饋酬賞迴路（路徑）（reward pathway）因各種因素而由另一回饋酬賞迴路（路徑）取代。
自閉症類群障礙（Autism Spectrum Disorder or Pervasive Development Disorder）當自閉症和注意力不足過動症同時存在時，社交溝通及社會互動障礙會更明顯，且出現固定興趣和重複行為，惟每位患者的嚴重程度不一。
網絡成癮症或3C成癮（Internet or 3C Product Addict）注意力不足過動症患者很容易分心，喜歡新鮮的事物和刺激，一旦進入網路世界，就很容易沉迷於無邊無際的網海。原本是為了要寫報告找資料，但是一看到有趣的訊息就忍不住點進去，然後又連到另一個網站，網網相連到天邊，患者或許知道本身已經分心，然而受限於自制力的缺乏，無法分辨事情的緩急輕重，於是乎很快就把報告和資料的事擱置或根本忘得一乾二淨。簡單易上手的遊戲，尤其影音畫面一直在變，充滿聲光效果的刺激，不斷破關和不停上升破紀錄的積分，可以輕易吸引他們的注意力，獲得立即的回饋和成就感，忘記日常生活中的挫折感和煩惱，因此網路和3C產品成癮乃注意力不足過動症患者需特別注意的問題。
利用核磁共振成像技術（MRI, Magnetic Resonance Imaging）對腦部掃描的研究顯示患有ADHD和正常孩子的圖象有分別。不少科學家認為這足以證明ADHD是和腦部創傷有關。但另一方面，根據腦部的正電子發射斷層掃描顯示，這種分別很可能只說明了ADHD患者的問題：因為他們並不能專注於一件事情，所以腦部影像只說明了作為腦內燃料的葡萄糖的分布，在兩組兒童之間的分別。在成人ADHD患者的腦掃描中，控制專注力的部份由於葡萄糖水平較低，所以顯得不太活躍（Zametkin et al.）。不過，沒有證據顯示低葡萄糖水平與低注意力有關連，亦無法推論兩者之間的因果關係。
不同的時期，描述注意力不足過動症的名詞也有所不同：在1952年的DSM-I稱為微細腦功能失常（minimal brain dysfunction），在1968年的DSM-II則稱為兒童活動亢進（hyperkinetic reaction of childhood），在1980年的DSM-III稱為注意力不足症（可能伴隨過動，也可能沒有）英文為 attention-deficit disorder (ADD) with or without hyperactivity，在1987年的DSM-III-R更名為注意力不足過動症，在1994年的DSM-IV將注意力不足過動症分為注意力散渙主導型（英語：Attention deficit hyperactivity disorder predominantly inattentive）、活動量過多型以及混合型，在2013年的DSM-5仍延用此一分類。其他的名詞有在1930年代使用的微細腦創傷（minimal brain damage），但因為不少病童都沒有發覺有受過任何創傷，因此後來改名為微細腦功能失常。
^Sibley, Margaret H.; Swanson, James M.; Arnold, L. Eugene; Hechtman, Lily T.; Owens, Elizabeth B.; Stehli, Annamarie; Abikoff, Howard; Hinshaw, Stephen P.; Molina, Brooke S. G.; Mitchell, John T.; Jensen, Peter S.; Howard, Andrea L.; Lakes, Kimberley D.; Pelham, William E. Defining ADHD symptom persistence in adulthood: optimizing sensitivity and specificity. Journal of Child Psychology and Psychiatry. 2016. doi:10.1111/jcpp.12620. ISSN 0021-9630.
^Margaret H. Sibley, James M. Swanson, L. Eugene Arnold, Lily T. Hechtman, Elizabeth B. Owens, Annamarie Stehli, Howard Abikoff, Stephen P. Hinshaw, Brooke S. G. Molina, John T. Mitchell, Peter S. Jensen, Andrea L. Howard, Kimberley D. Lakes & William E. Pelham. Defining ADHD symptom persistence in adulthood: optimizing sensitivity and specificity. Journal of child psychology and psychiatry, and allied disciplines. September 2016. doi:10.1111/jcpp.12620. PMID 27642116. CONCLUSION:The interview format optimizes young adult self-reporting when parent reports are not available. However, the combination of parent and self-reports from rating scales, using an 'or' rule and a NB threshold optimized the balance between sensitivity and specificity. With this definition, 60% of the ADHD group demonstrated symptom persistence and 41% met both symptom and impairment criteria in adulthood.
^Signs and symptoms of Attention Deficit Hyperactivity Disorder, National Institute of Mental Health.. nimh.nih.gov. National Institute of mental health. March 2013 [January 2017]（英語）. Many adolescents with ADHD also struggle with relationships and antisocial behaviors. Inattention, restlessness, and impulsivity tend to persist into adulthood. Symptoms of ADHD can be mistaken for emotional or disciplinary problems or missed entirely in quiet, well-behaved children, leading to a delay in diagnosis. Adults with undiagnosed ADHD may have a history of poor academic performance, problems at work, or difficult or failed relationships.
^ADHD symptom persistence into adulthood estimated. Science News. Journal of Child Psychology and Psychiatry, 2016. October 20, 2016 [January 2017]. （原始內容存檔於September 19, 2016） （英語）. There has been a lot of recent controversy over whether children with ADHD continue to experience symptoms into adulthood," said Dr. Margaret Sibley, lead author of the Journal of Child Psychology and Psychiatry study. "This study found that the way you diagnose ADHD can lead to different conclusions about whether or not an adult still has the disorder that started in childhood. First, if you ask the adult about their continued symptoms, they will often be unaware of them; however, family members or others who know them well often confirm that they still observe significant symptoms in the adult." Dr. Sibley added that if the classic childhood definition of ADHD is used when diagnosing adults, many cases will be missed because symptom presentation changes in adulthood. "By asking a family member about the adult's symptoms and using adult-based definitions of the disorder, you typically find that around half of children with moderate to severe ADHD still show significant signs of the disorder in adulthood.
^Frazier, TW; Demaree, HA; Youngstrom, EA (July 2004). "Meta-analysis of intellectual and neuropsychological test performance in attention-deficit/hyperactivity disorder.". Neuropsychology. 18 (3): 543–55. doi:10.1037/0894-418.104.22.1683. PMID 15291732.
^Mackenzie, GB; Wonders, E (2016). "Rethinking Intelligence Quotient Exclusion Criteria Practices in the Study of Attention Deficit Hyperactivity Disorder.". Frontiers in psychology. 7: 794. doi:10.3389/fpsyg.2016.00794. PMC 4886698Freely accessible. PMID 27303350.
^ 12.012.112.212.3Chan, Eugenia; Fogler, Jason M.; Hammerness, Paul G. Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents. JAMA. 2016, 315 (18): 1997. doi:10.1001/jama.2016.5453. ISSN 0098-7484. Findings Sixteen randomized clinical trials and 1 meta-analysis, involving 2668 participants, of pharmacological and psychosocial treatments for ADHD in adolescents aged 12 years to 18 years were included. Evidence of efficacy was stronger for the extended-release methylphenidate and amphetamine class stimulant medications (level 1B based on Oxford Centre for Evidence-Based Medicine criteria) and atomoxetine than for the extended-release α2-adrenergic agonists guanfacine or clonidine (no studies). For the primary efficacy measure of total symptom score on the ADHD Rating Scale (score range, 0 [least symptomatic] to 54 [most symptomatic]), both stimulant and nonstimulant medications led to clinically significant reductions of 14.93 to 24.60 absolute points. The psychosocial treatments combining behavioral, cognitive behavioral, and skills training techniques demonstrated small- to medium-sized improvements (range for mean SD difference in Cohen d, 0.30-0.69) for parent-rated ADHD symptoms, co-occurring emotional or behavioral symptoms, and interpersonal functioning. Psychosocial treatments were associated with more robust (Cohen d range, 0.51-5.15) improvements in academic and organizational skills, such as homework completion and planner use.
^ 13.013.1Chan, Eugenia; Fogler, Jason M.; Hammerness, Paul G. Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents. JAMA. 2016, 315 (18): 1997. doi:10.1001/jama.2016.5453. ISSN 0098-7484. Conclusions and Relevance Evidence supports the use of extended-release methylphenidate and amphetamine formulations, atomoxetine, and extended-release guanfacine to improve symptoms of ADHD in adolescents. Psychosocial treatments incorporating behavior contingency management, motivational enhancement, and academic, organizational, and social skills training techniques were associated with inconsistent effects on ADHD symptoms and greater benefit for academic and organizational skills. Additional treatment studies in adolescents, including combined pharmacological and psychosocial treatments, are needed..
^Coleman WL (August 2008). "Social competence and friendship formation in adolescents with attention-deficit/hyperactivity disorder". Adolesc Med State Art Rev. 19 (2): 278–99, x. PMID 18822833.
^"ADHD Anger Management Directory". Webmd.com. Retrieved 17 January 2014.
^"F90 Hyperkinetic disorders", International Statistical Classification of Diseases and Related Health Problems 10th Revision, World Health Organisation, 2010, retrieved 2 November 2014
^Bellani M, Moretti A, Perlini C, Brambilla P (December 2011). "Language disturbances in ADHD". Epidemiol Psychiatr Sci. 20 (4): 311–315. doi:10.1017/S2045796011000527. PMID 22201208.
^ 35.035.1Walitza, S; Drechsler, R; Ball, J (August 2012). "Das schulkind mit ADHS" [The school child with ADHD]. Ther Umsch (in German). 69 (8): 467–73. doi:10.1024/0040-5930/a000316. PMID 22851461.
^ 36.036.1Emond, V; Joyal, C; Poissant, H. Neuroanatomie structurelle et fonctionnelle du trouble déficitaire d』attention avec ou sans hyperactivité (TDAH) [Structural and functional neuroanatomy of attention-deficit hyperactivity disorder (ADHD)]. Encephale. April 2009, 35 (2): 107–14. doi:10.1016/j.encep.2008.01.005. PMID 19393378（法語）.
^ 38.038.1Dr. Hallowell on the Today show discussing Adult ADD. Drhallowell.com. 2014-10-16 [2016-12-09]. Dr. Hallowell on the Today show discussing Adult ADHD\ While ADHD tends to be associated with childhood, we』ve learned that it is far more widespread among adults than previously understood. While there are some children with ADHD who will outgrow it, we now know that the vast majority will not. Listed below are criteria for adult ADHD that we developed from our clinical experience: A sense of underachievement, of not meeting one’s goals , regardless of how much one has actually accomplished. Difficulty getting organized. Chronic procrastination or trouble getting started. Many projects going simultaneously; trouble with follow through. A tendency to say what comes to mind without necessarily considering the timing or appropriateness of the remark. A frequent search for high stimulation. An intolerance of boredom. Easy distractibility; trouble focusing attention, tendency to tune out or drift away in the middle of a page or conversation, often coupled with an inability to focus at times. Often creative, intuitive, highly intelligent. Trouble in going through established channels and following 「proper」 procedure. Impatient; low tolerance of frustration. Impulsive, either verbally or in action, as an impulsive spending of money. Changing plans, enacting new schemes or career plans and the like; hot-tempered. A tendency to worry needlessly, endlessly; a tendency to scan the horizon looking for something to worry about, alternating with attention to or disregard for actual dangers. A sense of insecurity. Mood swings, mood iability, especially when disengaged from a person or a project. Physical or cognitive restlessness. A tendency toward addictive behavior. Chronic problems with self-esteem. Inaccurate self-observation. Family history of ADHD or manic depressive illness or depression or substance abuse or other disorders of impulse control or mood.Recognizing and treating ADHD is just as important for adults as it is for children, as it has a wide ranging impact in careers, marriages and families.
^Bailey, Eileen. "ADHD and Learning Disabilities: How can you help your child cope with ADHD and subsequent Learning Difficulties? There is a way.". Remedy Health Media, LLC. Retrieved 15 November 2013.
^"Attention Deficit Hyperactivity Disorder (ADHD)". The National Institute of Mental Health (NIMH). Retrieved 15 November 2013.
^Hofvander B, Ossowski D, Lundström S, Anckarsäter H. Continuity of aggressive antisocial behavior from childhood to adulthood: The question of phenotype definition. Int J Law Psychiatry. 2009, 32 (4): 224–234. doi:10.1016/j.ijlp.2009.04.004. PMID 19428109.
^Rubia K. "Cool" inferior frontostriatal dysfunction in attention-deficit/hyperactivity disorder versus "hot" ventromedial orbitofrontal-limbic dysfunction in conduct disorder: a review. Biol. Psychiatry. June 2011, 69 (12): e69–87. doi:10.1016/j.biopsych.2010.09.023. PMID 21094938.
^[Wolraich M, Brown L, Brown RT, DuPaul G, Earls M, Feldman HM, Ganiats TG, Kaplanek B, Meyer B, Perrin J, Pierce K, Reiff M, Stein MT, Visser S (November 2011). "ADHD: clinical practice guideline for the diagnosis, evaluation, and treatment of attention-deficit/hyperactivity disorder in children and adolescents". Pediatrics. 128 (5): 1007–1022. doi:doi:10.1542%2Fpeds.2011-2654. PMID 22003063.PMID22003063.]
^Catalá-López, F; Peiró, S; Ridao, M; Sanfélix-Gimeno, G; Gènova-Maleras, R; Catalá, MA. Prevalence of attention deficit hyperactivity disorder among children and adolescents in Spain: a systematic review and meta-analysis of epidemiological studies.. BMC Psychiatry. Oct 12, 2012, 12: 168. doi:10.1186/1471-244X-12-168. PMID 23057832.
^National Collaborating Centre for Mental Health. Attention Deficit Hyperactivity Disorder: Diagnosis and Management of ADHD in Children, Young People and Adults. British Psychological Society. 2009: 19–27, 38, 130, 133, 317. ISBN 9781854334718.
^Burt SA. Rethinking environmental contributions to child and adolescent psychopathology: a meta-analysis of shared environmental influences. Psychol Bull. July 2009, 135 (4): 608–637. doi:10.1037/a0015702. PMID 19586164.
^Berry, MD. The potential of trace amines and their receptors for treating neurological and psychiatric diseases. Reviews on Recent Clinical Trials. January 2007, 2 (1): 3–19. doi:10.2174/157488707779318107. PMID 18473983. Although there is little direct evidence, changes in trace amines, in particular PE, have been identified as a possible factor for the onset of attention deficit/hyperactivity disorder (ADHD). … Further, amphetamines, which have clinical utility in ADHD, are good ligands at trace amine receptors. Of possible relevance in this aspect is modafanil, which has shown beneficial effects in ADHD patients and has been reported to enhance the activity of PE at TAAR1. Conversely, methylphenidate, …showed poor efficacy at the TAAR1 receptor. In this respect it is worth noting that the enhancement of functioning at TAAR1 seen with modafanil was not a result of a direct interaction with TAAR1.
^Burger PH, Goecke TW, Fasching PA, Moll G, Heinrich H, Beckmann MW, Kornhuber J. [How does maternal alcohol consumption during pregnancy affect the development of attention deficit/hyperactivity syndrome in the child]. Fortschr Neurol Psychiatr (Review). September 2011, 79 (9): 500–506. doi:10.1055/s-0031-1273360. PMID 21739408（German）.引文格式1維護：未識別語文類型 (link)
^de Cock M, Maas YG, van de Bor M. Does perinatal exposure to endocrine disruptors induce autism spectrum and attention deficit hyperactivity disorders? Review. Acta Paediatr. (Review. Research Support, Non-U.S. Gov't). August 2012, 101 (8): 811–818. doi:10.1111/j.1651-2227.2012.02693.x. PMID 22458970.
^Mayes R, Bagwell C, Erkulwater JL. Medicating Children: ADHD and Pediatric Mental Health illustrated. Harvard University Press. 2009: 4–24. ISBN 9780674031630.
^ 106.0106.1106.2106.3106.4106.5Sonuga-Barke EJ, Brandeis D, Cortese S, Daley D, Ferrin M, Holtmann M, Stevenson J, Danckaerts M, van der Oord S, Döpfner M, Dittmann RW, Simonoff E, Zuddas A, Banaschewski T, Buitelaar J, Coghill D, Hollis C, Konofal E, Lecendreux M, Wong IC, Sergeant J. Nonpharmacological interventions for ADHD: systematic review and meta-analyses of randomized controlled trials of dietary and psychological treatments. Am J Psychiatry. March 2013, 170 (3): 275–289. doi:10.1176/appi.ajp.2012.12070991. PMID 23360949. Free fatty acid supplementation and artificial food color exclusions appear to have beneficial effects on ADHD symptoms, although the effect of the former are small and those of the latter may be limited to ADHD patients with food sensitivities...
^CDC, Facts About ADHD, Centers for Disease Control and Prevention, 6 Jan 2016 [20 Mar 2016]
^ 109.0109.1Ertürk, E; Wouters, S; Imeraj, L; Lampo, A. Association of ADHD and Celiac Disease: What Is the Evidence? A Systematic Review of the Literature.. Journal of Attention Disorders (Review). 29 January 2016. doi:10.1177/1087054715611493. PMID 26825336. Up till now, there is no conclusive evidence for a relationship between ADHD and CD. Therefore, it is not advised to perform routine screening of CD when assessing ADHD (and vice versa) or to implement GFD as a standard treatment in ADHD. Nevertheless, the possibility of untreated CD predisposing to ADHD-like behavior should be kept in mind. ... It is possible that in untreated patients with CD, neurologic symptoms such as chronic fatigue, inattention, pain, and headache could predispose patients to ADHD-like behavior (mainly symptoms of inattentive type), which may be alleviated after GFD treatment. (CD: celiac disease; GFD: gluten-free diet)
^ 115.0115.1115.2115.3115.4115.5115.6115.7115.8115.9Malenka RC, Nestler EJ, Hyman SE. Chapters 10 and 13. (編) Sydor A, Brown RY. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience 2nd. New York: McGraw-Hill Medical. 2009: 266, 315, 318–323. ISBN 9780071481274. Early results with structural MRI show thinning of the cerebral cortex in ADHD subjects compared with age-matched controls in prefrontal cortex and posterior parietal cortex, areas involved in working memory and attention.
^ 116.0116.1116.2116.3116.4116.5116.6Malenka RC, Nestler EJ, Hyman SE. Chapter 6: Widely Projecting Systems: Monoamines, Acetylcholine, and Orexin. (編) Sydor A, Brown RY. Molecular Neuropharmacology: A Foundation for Clinical Neuroscience 2nd. New York: McGraw-Hill Medical. 2009: 148, 154–157. ISBN 9780071481274. DA has multiple actions in the prefrontal cortex. It promotes the "cognitive control" of behavior: the selection and successful monitoring of behavior to facilitate attainment of chosen goals. Aspects of cognitive control in which DA plays a role include working memory, the ability to hold information "on line" in order to guide actions, suppression of prepotent behaviors that compete with goal-directed actions, and control of attention and thus the ability to overcome distractions. Cognitive control is impaired in several disorders, including attention deficit hyperactivity disorder. ... Noradrenergic projections from the LC thus interact with dopaminergic projections from the VTA to regulate cognitive control. ... it has not been shown that 5HT makes a therapeutic contribution to treatment of ADHD. NOTE: DA: dopamine, LC: locus coeruleus, VTA: ventral tegmental area, 5HT: serotonin (5-hydroxytryptamine)
^Cortese S. The neurobiology and genetics of Attention-Deficit/Hyperactivity Disorder (ADHD): what every clinician should know. Eur. J. Paediatr. Neurol. September 2012, 16 (5): 422–433. doi:10.1016/j.ejpn.2012.01.009. PMID 22306277.
^ 123.0123.1Diamond A. Executive functions. Annu. Rev. Psychol. 2013, 64: 135–168. doi:10.1146/annurev-psych-113011-143750. PMC 4084861. PMID 23020641. EFs and prefrontal cortex are the first to suffer, and suffer disproportionately, if something is not right in your life. They suffer first, and most, if you are stressed (Arnsten 1998, Liston et al. 2009, Oaten & Cheng 2005), sad (Hirt et al. 2008, von Hecker & Meiser 2005), lonely (Baumeister et al. 2002, Cacioppo & Patrick 2008, Campbell et al. 2006, Tun et al. 2012), sleep deprived (Barnes et al. 2012, Huang et al. 2007), or not physically fit (Best 2010, Chaddock et al. 2011, Hillman et al. 2008). Any of these can cause you to appear to have a disorder of EFs, such as ADHD, when you do not.
^Modesto-Lowe V, Chaplin M, Soovajian V, Meyer A. Are motivation deficits underestimated in patients with ADHD? A review of the literature. Postgrad Med. 2013, 125 (4): 47–52. doi:10.3810/pgm.2013.07.2677. PMID 23933893. Behavioral studies show altered processing of reinforcement and incentives in children with ADHD. These children respond more impulsively to rewards and choose small, immediate rewards over larger, delayed incentives. Interestingly, a high intensity of reinforcement is effective in improving task performance in children with ADHD. Pharmacotherapy may also improve task persistence in these children. ... Previous studies suggest that a clinical approach using interventions to improve motivational processes in patients with ADHD may improve outcomes as children with ADHD transition into adolescence and adulthood.
^ 138.0138.1Combining medications could offer better results for ADHD patients. Science News. Elsevier. August 1, 2016 [January 2017]. （原始內容存檔於August 2016）. "Three studies to be published in the August 2016 issue of the Journal of the American Academy of Child and Adolescent Psychiatry (JAACAP) report that combining two standard medications could lead to greater clinical improvements for children with attention-deficit/hyperactivity disorder (ADHD) than either ADHD therapy alone.", August, 2016
^Label of Strattera consisting of atomoxetine. DailyMed.gov. Eli Lilly Company. June 2015 [February 2017]. DOSAGE AND ADMINISTRATION 2.1 Acute Treatment Dosing of children and adolescents up to 70 kg body weight — STRATTERA should be initiated at a total daily dose of approximately 0.5 mg/kg and increased after a minimum of 3 days to a target total daily dose of approximately 1.2 mg/kg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening. No additional benefit has been demonstrated for doses higher than 1.2 mg/kg/day [see Clinical Studies (14)]. 'The total daily dose in children and adolescents should not exceed 1.4 mg/kg or 100 mg, whichever is less'. Dosing of children and adolescents over 70 kg body weight and adults — STRATTERA should be initiated at a total daily dose of 40 mg and increased after a minimum of 3 days to a target total daily dose of approximately 80 mg administered either as a single daily dose in the morning or as evenly divided doses in the morning and late afternoon/early evening. 'After 2 to 4 additional weeks, the dose may be increased to a maximum of 100 mg in patients who have not achieved an optimal response'. There are no data that support increased effectiveness at higher doses [see Clinical Studies (14)]. The maximum recommended total daily dose in children and adolescents over 70 kg and adults is 100 mg.。
^Frequently Asked Questions. http://www.strattera.com/. Strattera-Eli Lilly. September 2016 [February 2017]. Strattera works gradually, so improvements are seen over time. When your child starts treatment with Strattera, it's important to set some small goals. Remember to be patient—some people notice small changes within 2 weeks, and by 4 to 6 weeks at target dose you should see significant improvement in your child's symptoms.
^3, 注意力不足過動症(PDF), 中華民國衛生福利部/心理衛生專輯 1 1, 中華民國衛生福利部/心理衛生專輯/03注意力不足過動症.pdf: 中華民國衛生福利部: 22, [June 2015], ISBN 9789860454154, （原始內容(PDF)存檔於June 2015） （Chinese Traditional and 繁體中文）, atomoxetine，用在病情 較為複雜、或是無法忍受MPH副作用的患者，然而一般發現其對於專注度的改善沒有MPH明顯引文格式1維護：未識別語文類型 (link)
^Parent's Medication Guide: ADHD(PDF). American Psychiatric Association. American Psychiatric Association & American Academy of Child and Adolescent Psychiatry (AACAP). July 2013 [January 2017]. （原始內容存檔於July 2013）. Though not FDA-approved for combined treatment, atomoxetine (Strattera) is sometimes used in conjunction with stimulants as an off-label combination therapy.
^Medical Encyclopedia → Attention deficit hyperactivity disorder. MedlinePlus.gov. 5 January 2017 [January 2017]. Medicine combined with behavioral treatment often works best. Different ADHD medicines can be used alone or combined with each other. The doctor will decide which medicine is right, based on the person's symptoms and needs.
^Label of Strattera consisting of atomoxetine. DailyMed.gov. Eli Lilly Company. June 2015 [February 2017]. 7.7 Methylphenidate\ Coadministration of methylphenidate with STRATTERA did not increase cardiovascular effects beyond those seen with methylphenidate alone.
^Parent's Medication Guide: ADHD(PDF). American Psychiatric Association. American Psychiatric Association & American Academy of Child and Adolescent Psychiatry (AACAP). July 2013 [January 2017]. （原始內容存檔於July 2013）. Extended release guanfacine (Intuniv) and extended release clonidine (Kapvay) are approved to be added to stimulant treatment when the stimulant doesn』t fully reduce the ADHD symptoms.
^Combining medications could offer better results for ADHD patients. Science News. Elsevier. August 1, 2016 [January 2017]. （原始內容存檔於August 2016）. Summary:Three studies report that combining two standard medications could lead to greater clinical improvements for children with attention-deficit/hyperactivity disorder (ADHD) than either ADHD therapy alone. At present, studies show that the use of several ADHD medications result in significant reductions in ADHD symptoms. However, so far there is no conclusive evidence that these standard drug treatments also improve long-term academic, social, and clinical outcomes.
^ 170.0170.1Chan, Eugenia; Fogler, Jason M.; Hammerness, Paul G. Treatment of Attention-Deficit/Hyperactivity Disorder in Adolescents. JAMA. 2016, 315 (18): 1997. doi:10.1001/jama.2016.5453. ISSN 0098-7484. Conclusions and Relevance Evidence supports the use of extended-release methylphenidate and amphetamine formulations, atomoxetine, and extended-release guanfacine to improve symptoms of ADHD in adolescents. Psychosocial treatments incorporating behavior contingency management, motivational enhancement, and academic, organizational, and social skills training techniques were associated with inconsistent effects on ADHD symptoms and greater benefit for academic and organizational skills. Additional treatment studies in adolescents, including combined pharmacological and psychosocial treatments, are needed..
^Chang, Zheng; Lichtenstein, Paul; Halldner, Linda; D'Onofrio, Brian; Serlachius, Eva; Fazel, Seena; Långström, Niklas; Larsson, Henrik. Stimulant ADHD medication and risk for substance abuse. Journal of Child Psychology and Psychiatry. 2014, 55 (8): 878–885. doi:10.1111/jcpp.12164. ISSN 0021-9630. Results_ADHD medication was not associated with increased rate of substance abuse. Actually, the rate during 2009 was 31% lower among those prescribed ADHD medication in 2006, even after controlling for medication in 2009 and other covariates (hazard ratio: 0.69; 95% confidence interval: 0.57–0.84). Also, the longer the duration of medication, the lower the rate of substance abuse. Similar risk reductions were suggested among children and when investigating the association between stimulant ADHD medication and concomitant short-term abuse.
^Chang, Zheng; Lichtenstein, Paul; Halldner, Linda; D'Onofrio, Brian; Serlachius, Eva; Fazel, Seena; Långström, Niklas; Larsson, Henrik. Stimulant ADHD medication and risk for substance abuse. Journal of Child Psychology and Psychiatry. 2014, 55 (8): 878–885. doi:10.1111/jcpp.12164. ISSN 0021-9630. Conclusions：We found no indication of increased risks of substance abuse among individuals prescribed stimulant ADHD medication; if anything, the data suggested a long-term protective effect on substance abuse. Although stimulant ADHD medication does not seem to increase the risk for substance abuse, clinicians should remain alert to the potential problem of stimulant misuse and diversion in ADHD patients.
^[Fabiano GA, Pelham WE, Coles EK, Gnagy EM, Chronis-Tuscano A, O'Connor BC (March 2009). "A meta-analysis of behavioral treatments for attention-deficit/hyperactivity disorder". Clin Psychol Rev. 29 (2): 129–140. doi:10.1016/j.cpr.2008.11.001. PMID 19131150.]
^Fabiano GA, Pelham WE, Coles EK, Gnagy EM, Chronis-Tuscano A, O'Connor BC. A meta-analysis of behavioral treatments for attention-deficit/hyperactivity disorder. Clin Psychol Rev. March 2009, 29 (2): 129–140. doi:10.1016/j.cpr.2008.11.001. PMID 19131150.
^Kratochvil CJ, Vaughan BS, Barker A, Corr L, Wheeler A, Madaan V. Review of pediatric attention deficit/hyperactivity disorder for the general psychiatrist. Psychiatr. Clin. North Am. March 2009, 32 (1): 39–56. doi:10.1016/j.psc.2008.10.001. PMID 19248915.
^Guidelines May Have Helped Curb ADHD Diagnoses in Preschoolers. MedlinePlus.gov. HealthDay. Tuesday, November 15, 2016 [January 2017]. （原始內容存檔於February twenty first, 2017.）. The guidelines, issued by the American Academy of Pediatrics (AAP), called for a standardized approach to diagnosis, and recommended behavior therapy -- not drugs -- as the first-line therapy for preschoolers.請檢查|date=, |archive-date=中的日期值 (幫助)
^Nigg JT, Lewis K, Edinger T, Falk M. Meta-analysis of attention-deficit/hyperactivity disorder or attention-deficit/hyperactivity disorder symptoms, restriction diet, and synthetic food color additives. J Am Acad Child Adolesc Psychiatry. January 2012, 51 (1): 86–97. doi:10.1016/j.jaac.2011.10.015. PMID 22176942.
^Krause J. SPECT and PET of the dopamine transporter in attention-deficit/hyperactivity disorder. Expert Rev. Neurother. April 2008, 8 (4): 611–625. doi:10.1586/1473722.214.171.1241. PMID 18416663. Zinc binds at ... extracellular sites of the DAT , serving as a DAT inhibitor. In this context, controlled double-blind studies in children are of interest, which showed positive effects of zinc [supplementation] on symptoms of ADHD [105,106]. It should be stated that at this time [supplementation] with zinc is not integrated in any ADHD treatment algorithm.
^Rick Nauert PhD. Music Lessons May Help Kids with Autism & ADHD. psychcentral.com. the Radiological Society of North America (RSNA). Novemeber 23rd, 2016 [January 2017]. A new imaging study suggests taking music lessons increases brain fiber connections in children. As such, the training may be useful in treating autism and attention-deficit hyperactivity disorder (ADHD), according to researchers from the Radiological Society of North America (RSNA).請檢查|date=中的日期值 (幫助)
^Palmer ED, Finger S. An early description of ADHD (inattentive subtype): Dr Alexander Crichton and 'Mental restlessness' (1798). Child and Adolescent Mental Health. May 2001, 6 (2): 66–73. doi:10.1111/1475-3588.00324.