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JFCR39：修订间差异

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'''{{PAGENAME}}'''是日本[[癌研究會]]（Japanese Foundation for Cancer Research，JFCR）列出的39种[[人类]]癌症[[细胞系]]的列表，用于[[抗癌药物]]筛选等[[科学研究]]<ref name=JFCR39>{{cite journal |last1=Kong |first1=D |last2=Yamori |first2=T |title=JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs. |journal=Bioorganic & medicinal chemistry |date=2012-03-15 |volume=20 |issue=6 |pages=1947-51 |doi=10.1016/j.bmc.2012.01.017 |pmid=22336246}}</ref>。与美国[[国家癌症研究所]]列出的[[NCI-60]]相比，JFCR39删去了所有[[白血病]]细胞系，但增加了[[胃癌]]细胞系，[[肺癌]]中不止列出[[非小细胞肺癌]]，也包括[[小细胞肺癌]]，还增加了几个来自日本病人的细胞系<ref name=JFCR39/>。JFCR后续又设立了只包括[[胃癌]]、[[肺癌]]与[[乳腺癌]]的JFCR45<ref name=JFCR45/>。
'''{{PAGENAME}}'''是日本[[癌研究會]]（Japanese Foundation for Cancer Research，JFCR）列出的39种[[人类]]癌症[[细胞系]]的列表，用于[[抗癌药物]]筛选等[[科学研究]]<ref name=JFCR39>{{cite journal |last1=Kong |first1=D |last2=Yamori |first2=T |title=JFCR39, a panel of 39 human cancer cell lines, and its application in the discovery and development of anticancer drugs. |journal=Bioorganic & medicinal chemistry |date=2012-03-15 |volume=20 |issue=6 |pages=1947-51 |doi=10.1016/j.bmc.2012.01.017 |pmid=22336246}}</ref>。与美国[[国家癌症研究所]]列出的[[NCI-60]]相比，JFCR39删去了所有[[白血病]]细胞系，但增加了[[胃癌]]细胞系，[[肺癌]]中不止列出[[非小细胞肺癌]]，也包括[[小细胞肺癌]]，还增加了几个来自日本病人的细胞系<ref name=JFCR39/>。JFCR后续又设立了只包括[[胃癌]]、[[肝癌]]与[[乳腺癌]]三类的JFCR45<ref name=JFCR45/>。


==细胞系==
==细胞系==
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| [[PLC/PRF/5]] || || [https://www.cellosaurus.org/CVCL_0485 CVCL_0485]
| [[PLC/PRF/5]] || || [https://www.cellosaurus.org/CVCL_0485 CVCL_0485]
|-
|-
| [[Huh7]] || <ref name="Sainz2009">{{cite journal|title=Three-dimensional ''Huh7'' cell culture system for the study of Hepatitis C virus infection|journal=Virology Journal|year=2009|volume=6|page=103|doi=10.1186/1743-422X-6-103|pmid=19604376|pmc=2719612|last1=Sainz|first1=Bruno|last2=Tencate|first2=Veronica|last3=Uprichard|first3=Susan L}}</ref> || [https://www.cellosaurus.org/CVCL_0336 CVCL_0336]
| [[Huh7]] || || [https://www.cellosaurus.org/CVCL_0336 CVCL_0336]
|-
|-
| [[HLE]] || || [https://www.cellosaurus.org/CVCL_1281 CVCL_1281]
| [[HLE]] || || [https://www.cellosaurus.org/CVCL_1281 CVCL_1281]
|-
|-
| [[]] || || [https://www.cellosaurus.org/CVCL_ CVCL_]
| [[HLF]] || || [https://www.cellosaurus.org/CVCL_2947 CVCL_2947]
|-
|-
| [[]] || || [https://www.cellosaurus.org/CVCL_ CVCL_]
| [[Huh6]] || || [https://www.cellosaurus.org/CVCL_4381 CVCL_4381]
|-
|-
| [[]] || || [https://www.cellosaurus.org/CVCL_ CVCL_]
| [[REB]] || || [https://www.cellosaurus.org/CVCL_4896 CVCL_4896]
|-
|-
| [[]] || || [https://www.cellosaurus.org/CVCL_ CVCL_]
| [[]] || || [https://www.cellosaurus.org/CVCL_ CVCL_]

2024年3月13日 (三) 07:37的版本

JFCR39是日本癌研究會（Japanese Foundation for Cancer Research，JFCR）列出的39种人类癌症细胞系的列表，用于抗癌药物筛选等科学研究[1]。与美国国家癌症研究所列出的NCI-60相比，JFCR39删去了所有白血病细胞系，但增加了胃癌细胞系，肺癌中不止列出非小细胞肺癌，也包括小细胞肺癌，还增加了几个来自日本病人的细胞系[1]。JFCR后续又设立了只包括胃癌、肝癌与乳腺癌三类的JFCR45[2]。

细胞系

肺癌

细胞系 类型 性别 倍增时间 也列入 文献 外部链接
NCI-H23 非小细胞肺癌 男 33.4h NCI-60 [3] CVCL_1547
NCI-H226 非小细胞肺癌 男 61h NCI-60 [3] CVCL_1544
NCI-H522 非小细胞肺癌 男 38.2h NCI-60 [3] CVCL_1567
NCI-H460 非小细胞肺癌 男 17.8h NCI-60 [3] CVCL_0459
A549 非小细胞肺癌 男 22.9h NCI-60 [4] CVCL_0023
DMS 273 小细胞肺癌 女 6.2 d [5] CVCL_1176
DMS 114 小细胞肺癌 男 27h NCI-60附加列表 [6] CVCL_1174

胃癌

细胞系 性别 倍增时间 也列入 文献 外部链接
St-4 ？ ？ JFCR45 [7] CVCL_H265
MKN-1 男 43-45h JFCR45 [8] CVCL_1415
MKN-7 男 64-66h JFCR45 [9] CVCL_1417
MKN-28 男 28-32h JFCR45 [8] CVCL_1416
MKN-45 女 30-33 h JFCR45 [9] CVCL_0434
MKN-74 男 42-46h JFCR45 [9] CVCL_2791

卵巢癌

细胞系 倍增时间 也列入 文献 外部链接
OVCAR-3 34.7h NCI-60 [10] CVCL_0465
OVCAR-4 41.4h NCI-60 [10] CVCL_1627
OVCAR-5 48.8h NCI-60 [10] CVCL_1628
OVCAR-8 26.1h NCI-60 [10] CVCL_1629
SK-OV-3 48.7h NCI-60 [11] CVCL_0532

肾癌

细胞系 性别 倍增时间 也列入 文献 外部链接
RXF-631L ? ? [12] CVCL_A780
ACHN 男 27.5h NCI-60 [13] CVCL_1067

黑色素瘤

细胞系 性别 倍增时间 也列入 文献 外部链接
LOX-IMVI 男 20.5h NCI-60 [14] CVCL_1381

结直肠癌

细胞系 性别 倍增时间 也列入 文献 外部链接
HCC-2998 未知 31.5h NCI-60 [3] CVCL_1266
KM12 男 23.7h NCI-60 [12] CVCL_1331
HT-29 女 19.5h NCI-60 [15] CVCL_0320
HCT 15 男 20.6h NCI-60 [16] CVCL_0292
HCT 116 男 17.4h NCI-60 [17] CVCL_0291

乳腺癌

细胞系 类型 倍增时间 也列入 文献 外部链接
HBC-4 ？ ？ JFCR45 [18] CVCL_B496
BSY-1 ？ ？ JFCR45 [18] CVCL_B499
HBC-5 ？ ？ JFCR45 [18] CVCL_B497
MCF-7 HR+ 25.4h JFCR45、ICBP43、NCI-60 [19] CVCL_0031
MDA-MB-231 三陰性乳癌 41.9h JFCR45、ICBP43、NCI-60 [20] CVCL_0062

脑癌

细胞系 性别 倍增时间 也列入 文献 外部链接
U-251MG 男 23.8h NCI-60 [21] CVCL_0021
SF-268 女 33.1h NCI-60 [22] CVCL_1689
SF-295 女 29.5h NCI-60 [3] CVCL_1690
SF-539 女 35.4h NCI-60 [3] CVCL_1691
SNB-75 女 62.8h NCI-60 [23] CVCL_1706
SNB-78 男 50h [23] CVCL_B321

前列腺癌

细胞系 性别 倍增时间 也列入 文献 外部链接
DU145 男 32.3h NCI-60 [24] CVCL_0105
PC-3 男 27.1h NCI-60 [25] CVCL_0035

JFCR45

日本癌研究会后续又设立了细胞系列表JFCR45，包括21种胃癌细胞系，12种肝癌细胞系与12种乳腺癌细胞系[2][26]：

胃肠道癌
细胞系 类型 性别 年龄 文献 外部链接
GCIY 胃腺癌 女 39Y [27] CVCL_1228
AZ-521 十二指肠腺癌 男 53Y [28] CVCL_2862
4-1st 胃腺癌 女 51Y [29] CVCL_L498
AGS 胃腺癌 女 54Y [30] CVCL_0139
ALF 胃癌 未知 未知 [31] CVCL_M035
TSG11 胃腺癌 女 46Y [32] CVCL_B477
ISt-1 胃癌 南 63Y [33] CVCL_F645
肺癌
细胞系 文献 外部链接
Hep G2（英语：Hep G2） [34] CVCL_0027
Hep 3B CVCL_0326
Li-7 CVCL_3840
PLC/PRF/5 CVCL_0485
Huh7 [35] CVCL_0336
HLE CVCL_1281
HLF CVCL_2947
Huh6 CVCL_4381
REB CVCL_4896
[[]] CVCL_
[[]] CVCL_
[[]] CVCL_
乳腺癌
细胞系 文献 外部链接
KPL-3C CVCL_E122
KPL-4 CVCL_5310
KPL-1 CVCL_2094
T-47D [36] CVCL_0553
HBC-9 CVCL_L497
ZR-75-1 [37] CVCL_0588
HBC-8 CVCL_L496

另见

参考文献

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取自“https://zh.wikipedia.org/w/index.php?title=JFCR39&oldid=81880176”