五味子素

五味子素（Schisandrins）是从五味子果实中提取的一类生物活性物质。^[1]研究显示其有脂联素受体2（ADIPOR2）激动剂的作用。^[2]主要包括五味子素A，五味子素B（γ-五味子素）与五味子素C。五味子素能够调节神经系统的兴奋性，增加抑制性神经递质γ-氨基丁酸（GABA）的含量，减少谷氨酸的含量，能够宁心安神，因此具有镇静催眠作用

参考资料

^ Park, SY; Park, SJ; Park, TG; Rajasekar, S; Lee, SJ; Choi, YW. Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia. International immunopharmacology. 2013, 17 (2): 415–26. PMID 23859871. doi:10.1016/j.intimp.2013.06.032.
^ Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay. PLOS ONE. 2013, 8 (5): e63354. PMC 3653934 . PMID 23691032. doi:10.1371/journal.pone.0063354.

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[1] Park, SY; Park, SJ; Park, TG; Rajasekar, S; Lee, SJ; Choi, YW. Schizandrin C exerts anti-neuroinflammatory effects by upregulating phase II detoxifying/antioxidant enzymes in microglia. International immunopharmacology. 2013, 17 (2): 415–26. PMID 23859871. doi:10.1016/j.intimp.2013.06.032.

[2] Sun Y, Zang Z, Zhong L, Wu M, Su Q, Gao X, Zan W, Lin D, Zhao Y, Zhang Z. Identification of adiponectin receptor agonist utilizing a fluorescence polarization based high throughput assay. PLOS ONE. 2013, 8 (5): e63354. PMC 3653934 . PMID 23691032. doi:10.1371/journal.pone.0063354.

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