臟器逆位
外观
(重定向自内脏逆位)
臟器逆位 situs inversus | |
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臟器逆位造成心臟及肺臟呈現鏡像對稱. | |
分类和外部资源 | |
醫學專科 | 醫學遺傳學 |
ICD-11 | LA82 |
ICD-9-CM | 759.3 |
OMIM | 270100 |
DiseasesDB | 29885 |
eMedicine | 413679 |
臟器逆位(situs inversus,situs transversus)亦稱內臟反位[1](situs oppositus),是一種先天性的結構缺陷,症狀是患者的內臟各器官的位置與一般人正好左右相反(鏡像顛倒),譬如患者的心臟位在右手邊,肝臟位在左手邊。這種先天缺陷現象較罕見,大约萬人裡才有一個(1/10000)[2]。
臟器逆位一般與常染色體隱性基因有關,此外,患有先天性心臟病患病的比率相對偏高,患者的健康狀況一般與普通人無甚明顯區別,許多患者是一直到自己的X光片才知道自己的內臟位置與其他人不一樣,且呈現鏡像對稱現象。[3]
註釋
[编辑]- ^ 存档副本. [2023-12-22]. (原始内容存档于2023-12-22).
- ^ Eitler, Katalin; Bibok, András; Telkes, Gábor. Situs Inversus Totalis: A Clinical Review. International Journal of General Medicine. 2022-03-03, 15 [2023-11-06]. ISSN 1178-7074. PMC 8901252
. PMID 35264880. doi:10.2147/IJGM.S295444. (原始内容存档于2023-11-07).
- ^ Situs Inversus Imaging: Overview, Radiography, Computed Tomography. 26 April 2016 [2019-04-09]. (原始内容存档于2019-09-03) –通过eMedicine.
延伸閱讀
[编辑]- McManus, Chris. Right Hand, Left Hand. Harvard University Press. 2002. ISBN 0-674-00953-3. this book was the 2003 Aventis winner and has a description of the history behind the discovery of thisTemplate:Vague medical condition.
- Yokoyama T, Copeland NG, Jenkins NA, Montgomery CA, Elder FF, Overbeek PA. Reversal of left-right asymmetry: a situs inversus mutation. Science. 1993, 260 (5108): 679–682. PMID 8480178. doi:10.1126/science.8480178.
- Lowe LA, Supp DM, Sampath K, et al. Conserved left-right asymmetry of nodal expression and alterations in murine situs inversus. Nature. 1996, 381 (6578): 158–161. PMID 8610013. doi:10.1038/381158a0.
- Levin M. Left-right asymmetry in vertebrate embryogenesis. BioEssays. 1997, 19 (4): 287–296. PMID 9136626. doi:10.1002/bies.950190406.
- Levin M, Pagan S, Roberts DJ, Cooke J, Kuehn MR, Tabin CJ. Left/right patterning signals and the independent regulation of different aspects of situs in the chick embryo. Dev. Biol. 1997, 189 (1): 57–67. PMID 9281337. doi:10.1006/dbio.1997.8662.
- Logan M, Pagán-Westphal SM, Smith DM, Paganessi L, Tabin CJ. The transcription factor Pitx2 mediates situs-specific morphogenesis in response to left-right asymmetric signals. Cell. 1998, 94 (3): 307–317. PMID 9708733. doi:10.1016/S0092-8674(00)81474-9.
- Stern CD, Wolpert L. Left-right asymmetry: all hands to the pump. Curr. Biol. 2002, 12 (23): R802–803. PMID 12477404. doi:10.1016/S0960-9822(02)01312-X.
外部連結
[编辑]
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- 放射学协作超文本:00698
- Chest X-ray & CT scan Radiology Teaching File