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曼陀罗萜醇酮

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曼陀罗萜醇酮
IUPAC名
(4aR,5R,6aR,6bS,8aR,12aR,14aR,14bR)-5-Hydroxy-4,4,6a,6b,8a,14b-hexamethyl-1,4,4a,5,6,6a,6b,7,8,8a,9,10,11,12,12a,14,14a,14b-octadecahydropicen-3(2H)-one
识别
CAS号 41498-80-0
PubChem 122859
ChemSpider 109521
SMILES
 
  • CC1(CCC2(CCC3(C(=CCC4C3(CC(C5C4(CCC(=O)C5(C)C)C)O)C)C2C1)C)C)C
性质
化学式 C30H48O2
摩尔质量 440.7 g·mol−1
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

曼陀罗萜醇酮(英語:Daturaolone,也称作:3-氧代-6-β-羟基-β-香树脂醇3-oxo-6-β-hydroxy-β-amyrin[1],化学名:6-羟基齐墩果-12-烯-3-酮6-hydroxyolean-12-en-3-one)是一种齐墩果烷型五环三萜化合物[2],化学式为C30H48O2,存在于曼陀罗D. stramonium[3]毛曼陀罗D. innoxia[4]曼陀罗属Datura)植物中。

参考文献

[编辑]
  1. ^ Bawazeer, Saud; Rauf, Abdur; Bawazeer, Sami. Gastrointestinal Motility, Muscle Relaxation, Antipyretic and Acute Toxicity Screening of Amyrin Type Triterpenoid (Daturaolone) Isolated From Datura metel Linnaeus (Angel's Trumpet) Fruits. Frontiers in Pharmacology. 2020, 11: 544794. ISSN 1663-9812. PMC 7546419可免费查阅. PMID 33101017. doi:10.3389/fphar.2020.544794可免费查阅. 
  2. ^ Baig, Muhammad Waleed; Fatima, Humaira; Akhtar, Nosheen; Hussain, Hidayat; Okla, Mohammad K.; Al-Hashimi, Abdulrahman; Al-Qahtani, Wahidah H.; AbdElgawad, Hamada; Haq, Ihsan-ul. Anti-Inflammatory Potential of Daturaolone from Datura innoxia Mill.: In Silico, In Vitro and In Vivo Studies. Pharmaceuticals. 2021-11-30, 14 (12): 1248. ISSN 1424-8247. PMC 8708807可免费查阅. PMID 34959649. doi:10.3390/ph14121248可免费查阅. 
  3. ^ Li J, Lin B, Wang G, Gao H, Qin M. [Chemical constituents of Datura stramonium seeds]. Zhongguo Zhong Yao Za Zhi = Zhongguo Zhongyao Zazhi = China Journal of Chinese Materia Medica. February 2012, 37 (3): 319–22. PMID 22568232 (中文). 
  4. ^ Kocór M, Pyrek JS, Atal CK, Bedi KL, Sharma BR. Triterpenes of Datura innoxia Mill. Structure of daturadiol and daturaolone. The Journal of Organic Chemistry. October 1973, 38 (21): 3685–8. PMID 4745874. doi:10.1021/jo00961a005.