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1-叠氮丙烷

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n-Propyl azide
Skeletal formula of propyl azide
Ball-and-stick model of the propyl azide molecule
IUPAC名
1-Azidopropane
别名 1-叠氮基丙烷
叠氮正丙烷
识别
CAS号 22293-25-0  checkY
PubChem 12405072
ChemSpider 14073926
SMILES
 
  • [N-]=[N+]=NCCC
InChI
 
  • 1/C3H7N3/c1-2-3-5-6-4/h2-3H2,1H3
InChIKey TVPPZASKIXGUJQ-UHFFFAOYAK
性质
化学式 C3H7N3
摩尔质量 85.11 g·mol−1
密度 0.8859 g·cm−3(20 °C)[1]
沸点 79 °C(352 K)[2]
81—82 °C(354—355 K)[3]
危险性
主要危害 有害;易爆
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

1-叠氮丙烷是一种有机化合物,化学式为C3H7N3。它可由1-溴丙烷叠氮化钠H2O-THF中回流反应得到。[3]它可用于合成三唑类化合物,如和丙炔反应,得到1-丙基-4-甲基-1H-1,2,3-三唑[4];和乙酰乙酸乙酯反应,得到1-丙基-5-甲基-1H-1,2,3-三唑-4-甲酸乙酯[5]

参考文献

[编辑]
  1. ^ Stolyarov, B. V.; Shavarda, A. L. Synthesis of alkyl azides in a preparative gas-chromatographic column. Zhurnal Organicheskoi Khimii, 1978. 14 (1): 202-203. ISSN: 0514-7492.
  2. ^ Lieber, Eugene; Ramachandra Rao, C. N.; Chao, Tai Siang; Wahl, Werner H. Physical studies on organic azides. Journal of Scientific & Industrial Research, 1957. 16B: 95-97. ISSN: 0022-4456.
  3. ^ 3.0 3.1 M. Swetha, P. Venkata Ramana, S. G. Shirodkar. Simple and Efficient Method for the Synthesis of Azides in Water-THF Solvent System. Organic Preparations and Procedures International. 2011-01, 43 (4): 348–353 [2021-01-12]. ISSN 0030-4948. doi:10.1080/00304948.2011.594002 (英语). 
  4. ^ Fangyong Yan, Michael Lartey, Kuldeep Jariwala, Sage Bowser, Krishnan Damodaran, Erik Albenze, David R. Luebke, Hunaid B. Nulwala, Berend Smit, Maciej Haranczyk. Toward a Materials Genome Approach for Ionic Liquids: Synthesis Guided by Ab Initio Property Maps. The Journal of Physical Chemistry B. 2014-11-26, 118 (47): 13609–13620 [2021-01-12]. ISSN 1520-6106. doi:10.1021/jp506972w (英语). 
  5. ^ Zhen-Jun Wang, Yang Gao, Yan-Ling Hou, Cheng Zhang, Shu-Jing Yu, Qiang Bian, Zheng-Ming Li, Wei-Guang Zhao. Design, synthesis, and fungicidal evaluation of a series of novel 5-methyl-1H-1,2,3-trizole-4-carboxyl amide and ester analogues. European Journal of Medicinal Chemistry. 2014-10, 86: 87–94 [2021-01-12]. doi:10.1016/j.ejmech.2014.08.029. (原始内容存档于2020-02-12) (英语).