is a city in the Apulia region of Italy, the capital of the province of Brindisi, off the coast of the Adriatic Sea. Historically, the city has played an important role in commerce and culture, due to its position on the Italian Peninsula and its natural port on the Adriatic Sea. The city is a major port for trade with Greece and the Middle East. Brindisi has an active industry in agriculture, chemical and energy production.