2-氟-6-氯苄胺
外觀
2-氟-6-氯苄胺 | |
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別名 | 2-氯-6-氟苄胺 2-氟-6-氯苯甲胺 |
識別 | |
CAS號 | 15205-15-9 ![]() |
性質 | |
化學式 | C7H7ClFN |
摩爾質量 | 159.59 g·mol−1 |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
2-氟-6-氯苄胺是一種有機化合物,化學式為C7H7ClFN,它可用於合成氟腺呤以及含2-氟-6-氯苯基的噁唑類PDE4抑制劑。[1][2]它可由2-氟-6-氯苯甲腈的還原反應製得。[3]
參考文獻
[編輯]- ^ Merck & Co. R. J. Tull, G. D. Hartman, and L. M. Weinstock, U.S. Patent 4,098,787 (1978).
- ^ Rongze Kuang, Ho-Jane Shue, Li Xiao, David J. Blythin, Neng-Yang Shih, Xiao Chen, Danlin Gu, John Schwerdt, Ling Lin, Pauline C. Ting, Jianhua Cao, Robert Aslanian, John J. Piwinski, Daniel Prelusky, Ping Wu, Ji Zhang, Xiang Zhang, Chander S. Celly, Motasim Billah, Peng Wang. Discovery of oxazole-based PDE4 inhibitors with picomolar potency. Bioorganic & Medicinal Chemistry Letters. 2012-04, 22 (7): 2594–2597 [2021-12-21]. doi:10.1016/j.bmcl.2012.01.115. (原始內容存檔於2020-02-13) (英語).
- ^ Steven Holshouser, Matthew Dunworth, Tracy Murray-Stewart, Yuri K. Peterson, Pieter Burger, Joy Kirkpatrick, Huan-Huan Chen, Robert A. Casero, Patrick M. Woster. Dual inhibitors of LSD1 and spermine oxidase. MedChemComm. 2019, 10 (5): 778–790 [2021-12-21]. ISSN 2040-2503. PMC 6533887
. PMID 31191868. doi:10.1039/C8MD00610E (英語).