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丹葉大黃素

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丹葉大黃素
Chemical structure of rhapontigenin
IUPAC名
5-[(E)-2-(3-Hydroxy-4-methoxyphenyl)ethen-1-yl]benzene-1,3-diol
別名 Protigenin
3,3',5-trihydroxy-4'-methoxystilbene
piceatannol 4'-methyl ether
識別
CAS號 500-65-2  checkY
PubChem 5320954
ChemSpider 4478875
SMILES
 
  • COc1ccc(cc1O)\C=C\c(cc2O)cc(O)c2
InChI
 
  • 1S/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+
InChIKey PHMHDRYYFAYWEG-NSCUHMNNSA-N
性質
化學式 C15H14O4
摩爾質量 258.27 g/mol g·mol⁻¹
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

丹葉大黃素(英語:Rhapontigenin)是一種芪類有機化合物,分子式C15H14O4,存在於紫葛(學名:Vitis coignetiae)和閉苞買麻藤(學名:Gnetum cleistostachyum)中[1],能抑制人CYP1A1[2]

參考文獻

[編輯]
  1. ^ Stilbenes from Gnetum cleistostachyum. Yao Chun-Suo, Lin Mao, LIiu Xin and Wang Ying-Hong, Huaxue xuebao, 2003, volume 61, no 8, pages 1331-1334, INIST法語Institut de l'information scientifique et technique:15332136
  2. ^ Chun, YJ; Ryu, SY; Jeong, TC; Kim, MY. Mechanism-based inhibition of human cytochrome P450 1A1 by rhapontigenin.. Drug metabolism and disposition: the biological fate of chemicals. 2001-04, 29 (4 Pt 1): 389–93. PMID 11259321.