二硫代熒光素

二硫代熒光素
	IUPAC名; 3′,6′-Bis(sulfanyl)spiro[2-benzofuran-3,9′-xanthene]-1-one
別名	巰基熒光素
識別
CAS號	25319-73-7
PubChem	91396
ChemSpider	82528
SMILES	C1=CC=C2C(=C1)C(=O)OC23C4=C(C=C(C=C4)S)OC5=C3C=CC(=C5)S;
性質
化學式	C20H12O3S2
摩爾質量	364.44 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

二硫代熒光素（英語：dithiofluorescein），也可稱為巰基熒光素（英語：thiofluorescein）是一種有機化合物，在分析化學中常用作絡合指示劑。本身為藍色，與二價汞離子（Hg²⁺）會生成無色的絡合物^[1]，因此可用在2-(羥基汞基)苯甲酸或2-(羥基汞基)苯甲酸鈉滴定硫醇中充當終點指示劑^[2]^[3]。二硫代熒光素能通過聚合物固定到光纖上，用於開發硫離子（S^2-）液流檢測器^[4]。不像熒光素和熒烷類染料分子中苯環取代基為羥基，二硫代熒光素分子中苯環取代基為巰基，不具備熒光性質^[5]。

參考文獻[編輯]

^ Wroński, Mieczysław. Determination of thiol esters with o-hydroxymercuribenzoic acid. Analyst. 1966, 19 (2): 745–746. doi:10.1039/AN9669100745.
^ Wroński, Mieczysław. Analytical applications of o-hydroxymercuribenzoic acid, dithiofluorescein and mercurated fluorescein. Talanta. 1977, 24 (6): 347–354. PMID 18962100. doi:10.1016/0039-9140(77)80019-2.
^ Chromý, V.; Svoboda, V. The determination of thiomalic acid. Talanta. 1963, 10 (10): 1109–1111. doi:10.1016/0039-9140(63)80152-6.
^ Narayanaswamy, Ramaier; Sevilla, Fortunato III. Flow cell studies with immobilised reagents for the development of an optical fibre sulphide sensor. Analyst. 1986, 111 (9): 1085. doi:10.1039/AN9861101085.
^ Sauer, Markus; Hofkens, Johan; Enderlein, Jörg. 2.2. Organic Fluorophores. Handbook of Fluorescence Spectroscopy and Imaging: From Ensemble to Single Molecules. 2011: 35–38. ISBN 978-3-527-31669-4.

[1] Wroński, Mieczysław. Determination of thiol esters with o-hydroxymercuribenzoic acid. Analyst. 1966, 19 (2): 745–746. doi:10.1039/AN9669100745.

[2] Wroński, Mieczysław. Analytical applications of o-hydroxymercuribenzoic acid, dithiofluorescein and mercurated fluorescein. Talanta. 1977, 24 (6): 347–354. PMID 18962100. doi:10.1016/0039-9140(77)80019-2.

[3] Chromý, V.; Svoboda, V. The determination of thiomalic acid. Talanta. 1963, 10 (10): 1109–1111. doi:10.1016/0039-9140(63)80152-6.

[4] Narayanaswamy, Ramaier; Sevilla, Fortunato III. Flow cell studies with immobilised reagents for the development of an optical fibre sulphide sensor. Analyst. 1986, 111 (9): 1085. doi:10.1039/AN9861101085.

[5] Sauer, Markus; Hofkens, Johan; Enderlein, Jörg. 2.2. Organic Fluorophores. Handbook of Fluorescence Spectroscopy and Imaging: From Ensemble to Single Molecules. 2011: 35–38. ISBN 978-3-527-31669-4.

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