9-甲基鳥嘌呤
外觀
9-甲基鳥嘌呤 | |
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識別 | |
CAS號 | 5502-78-3 ![]() |
性質 | |
化學式 | C6H7N5O |
摩爾質量 | 165.15 g·mol−1 |
外觀 | 白色固體[1] |
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。 |
9-甲基鳥嘌呤(9-MeG)是甲基鳥嘌呤的同分異構體之一,化學式為C6H7N5O。它可由N-甲基咪唑-4-酰胺-5-硫脲在氫氧化鈉溶液(1 N)中與乙酸銅回流製得。[1]它和三溴三羰基合錸(I)酸四乙銨在水中於50 °C反應,可以得到[Re(9-MeG-κN7)2(H2O)(CO)3]Br·H2O。[2]它在乙酸中和溴反應,可以得到8-溴-9-甲基鳥嘌呤。[3]
參考文獻
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- ^ Fabio Zobi, Olivier Blacque, Helmut W. Schmalle, Bernhard Spingler, Roger Alberto. Head-to-Head (HH) and Head-to-Tail (HT) Conformers of cis -Bis Guanine Ligands Bound to the [Re(CO) 3 ] + Core. Inorganic Chemistry. 2004-03-01, 43 (6): 2087–2096 [2022-09-01]. ISSN 0020-1669. doi:10.1021/ic035012a. (原始內容存檔於2022-09-01) (英語).
- ^ Nelly A. Fosu-Mensah, Wen Jiang, Andrea Brancale, Jun Cai, Andrew D. Westwell. The discovery of purine-based agents targeting triple-negative breast cancer and the αB-crystallin/VEGF protein–protein interaction. Medicinal Chemistry Research. 2019-02, 28 (2): 182–202 [2022-09-01]. ISSN 1054-2523. doi:10.1007/s00044-018-2275-9 (英語).