HU大麻素列表
耶路撒冷希伯來大學（Hebrew University）的拉斐爾·梅舒朗研究小組合成了上百種大麻素，其中一些是[1]：
| 名稱 | 類別 | 分子式 | Ki/nM (CB1) | Ki/nM (CB2) | 選擇性 | 結構 |
|---|---|---|---|---|---|---|
| HU-210 | 二苯並吡喃 | C25H38O3 | 0.23 | CB1 | 
| |
| HU-211 | 二苯並吡喃 | C25H38O3 | CB2 | 
| ||
| HU-239 | 二苯並吡喃 | C25H36O4 | 
| |||
| HU-243 | 二苯並吡喃 | C25H40O3 | 
| |||
| HU-308 | 聯苯 | C27H42O3 | 
| |||
| HU-320 | 聯苯 | C25H36O4 | 
| |||
| HU-331 | 聯苯 | C21H28O3 | 
| |||
| HU-336 | 二苯並吡喃 | C21H28O3 | 
| |||
| HU-345 | 二苯並吡喃 | C21H24O3 | 
| |||
| HU-474 | 聯苯[2] | C21H29FO2 | ||||
| HU-910 | 聯苯[2] | C27H42O3 | 1400[3] | 6[3] | CB2 |
參見
[編輯]參考文獻
[編輯]- ^ Howlett, AC; Champion, TM; Wilken, GH; Mechoulam, R. Stereochemical effects of 11-OH-delta 8-tetrahydrocannabinol-dimethylheptyl to inhibit adenylate cyclase and bind to the cannabinoid receptor. Neuropharmacology. February 1990, 29 (2): 161–5. PMID 2158635. S2CID 28602221. doi:10.1016/0028-3908(90)90056-W.
- ^ 2.0 2.1 Dos Santos Pereira, M; Maitan Santos, B; Gimenez, R; Guimarães, FS; Raisman-Vozari, R; Del Bel, E; Michel, PP. The two synthetic cannabinoid compounds 4'-F-CBD and HU-910 efficiently restrain inflammatory responses of brain microglia and astrocytes.. Glia. 2024-03, 72 (3): 529–545. PMID 38013496. doi:10.1002/glia.24489.
- ^ 3.0 3.1 Horváth, B; Magid, L; Mukhopadhyay, P; Bátkai, S; Rajesh, M; Park, O; Tanchian, G; Gao, RY; Goodfellow, CE; Glass, M; Mechoulam, R; Pacher, P. A new cannabinoid CB2 receptor agonist HU-910 attenuates oxidative stress, inflammation and cell death associated with hepatic ischaemia/reperfusion injury.. British journal of pharmacology. 2012-04, 165 (8): 2462–78. PMID 21449982. doi:10.1111/j.1476-5381.2011.01381.x.