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16α-氰基孕酮

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16α-氰基孕酮
IUPAC名
3β-Hydroxy-20-oxopregn-5-ene-16α-carbonitrile
系统名
(1S,2R,3as,3bS,7S,9aR,9bS,11aS)-1-Acetyl-7-hydroxy-9a,11a-dimethyl-2,3,3a,3b,4,6,7,8,9,9a,9b,10,11,11a-tetradecahydro-1H-cyclopenta[a]phenanthrene-2-carbonitrile
识别
CAS号 1434-54-4  checkY
PubChem 15032
ChemSpider 14308
SMILES
 
  • CC(=O)[C@H]1[C@@H](C[C@@H]2[C@@]1(CC[C@H]3[C@H]2CC=C4[C@@]3(CC[C@@H](C4)O)C)C)C#N
InChI
 
  • 1/C22H31NO2/c1-13(24)20-14(12-23)10-19-17-5-4-15-11-16(25)6-8-21(15,2)18(17)7-9-22(19,20)3/h4,14,16-20,25H,5-11H2,1-3H3/t14-,16-,17+,18-,19-,20-,21-,22-/m0/s1
InChIKey VSBHRRMYCDQLJF-ZDNYCOCVBP
IUPHAR配体 2762
性质
化学式 C22H31NO2
摩尔质量 341.49 g/mol g·mol⁻¹
若非注明,所有数据均出自标准状态(25 ℃,100 kPa)下。

16α-氰基孕酮(英语:Pregnenolone 16α-carbonitrile,缩写为PCN)是一种含氮有机化合物,分子式C22H31NO2,是一种人工合成的甾体抗糖皮质激素英语Antiglucocorticoid,也是孕甾烷X受体英语Pregnane X receptor激动剂[1][2][3]

参考文献

[编辑]
  1. ^ J.I. Mason. Genetics of Steroid Biosynthesis and Function. CRC Press. 2 September 2003: 449–. ISBN 978-0-203-30149-4. 
  2. ^ Giacinto Bagetta; Marco Cosentino; Marie Tiziana Corasaniti; Shinobu Sakurada. Herbal Medicines: Development and Validation of Plant-derived Medicines for Human Health. CRC Press. 19 April 2016: 250–. ISBN 978-1-4398-3769-6. 
  3. ^ Larisa Y. Poluektova; J. Victor Garcia-Martinez; Yoshio Koyanagi; Markus G. Manz; Andrew M. Tager. Humanized Mice for HIV Research. Springer. 18 February 2015: 350–. ISBN 978-1-4939-1655-9.