Daoy细胞

Daoy（ATCC编号HTB-186^[1]）是永生的人类原发性髓母细胞瘤细胞系，最初在1985年分离自一名4岁的白人男性癌症患者的小脑^[2]，经培养的细胞在裸鼠中很容易致瘤，并且迅速生长及易于传代，其蛋白质组和表型目前已应用于多项研究^[3]^[4]^[5]。有研究利用DAOY细胞模型，确定萝卜硫素（英语：Sulforaphane）是成神经管细胞瘤细胞凋亡的新型诱导剂^[6]。

参考资料

^ HTB-186. ATCC. [2019-12-18]. （原始内容存档于2019-12-18）.
^ Jacobsen, PF; Jenkyn, DJ; Papadimitriou, JM. Establishment of a human medulloblastoma cell line and its heterotransplantation into nude mice.. Journal of neuropathology and experimental neurology. 1985-09, 44 (5): 472–85 [2019-12-18]. PMID 2993532. doi:10.1097/00005072-198509000-00003. （原始内容存档于2019-12-18）.
^ Martelli, C; D'Angelo, L; Barba, M; Baranzini, M; Inserra, I; Iavarone, F; Vincenzoni, F; Tamburrini, G; Massimi, L; Rocco, CD; Caldarelli, M; Messana, I; Michetti, F; Castagnola, M; Lattanzi, W; Desiderio, C. Top-down proteomic characterization of DAOY medulloblastoma tumor cell line.. EuPA open proteomics. 2016-09, 12: 13–21 [2019-12-18]. PMID 29900115. doi:10.1016/j.euprot.2016.03.015. （原始内容存档于2019-12-18）.
^ Peyrl, A; Krapfenbauer, K; Slavc, I; Yang, JW; Strobel, T; Lubec, G. Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and principles.. Proteomics. 2003-09, 3 (9): 1781–800 [2019-12-18]. PMID 12973738. doi:10.1002/pmic.200300460. （原始内容存档于2019-12-18）.
^ Srivastava, VK; Nalbantoglu, J. Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer stem-like phenotype.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2008-10, 73 (10): 940–8 [2019-12-18]. PMID 18773455. doi:10.1002/cyto.a.20633. （原始内容存档于2019-12-18）.
^ Gingras, D; Gendron, M; Boivin, D; Moghrabi, A; Théorêt, Y; Béliveau, R. Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables.. Cancer letters. 2004-01-08, 203 (1): 35–43 [2019-12-18]. PMID 14670615. doi:10.1016/j.canlet.2003.08.025. （原始内容存档于2019-12-18）.

外部链接

Cellosaurus entry for Daoy（页面存档备份，存于互联网档案馆）

这是一篇分子与细胞生物学（分子细胞生物学）小作品。您可以通过编辑或修订扩充其内容。

[1] HTB-186. ATCC. [2019-12-18]. （原始内容存档于2019-12-18）.

[2] Jacobsen, PF; Jenkyn, DJ; Papadimitriou, JM. Establishment of a human medulloblastoma cell line and its heterotransplantation into nude mice.. Journal of neuropathology and experimental neurology. 1985-09, 44 (5): 472–85 [2019-12-18]. PMID 2993532. doi:10.1097/00005072-198509000-00003. （原始内容存档于2019-12-18）.

[3] Martelli, C; D'Angelo, L; Barba, M; Baranzini, M; Inserra, I; Iavarone, F; Vincenzoni, F; Tamburrini, G; Massimi, L; Rocco, CD; Caldarelli, M; Messana, I; Michetti, F; Castagnola, M; Lattanzi, W; Desiderio, C. Top-down proteomic characterization of DAOY medulloblastoma tumor cell line.. EuPA open proteomics. 2016-09, 12: 13–21 [2019-12-18]. PMID 29900115. doi:10.1016/j.euprot.2016.03.015. （原始内容存档于2019-12-18）.

[4] Peyrl, A; Krapfenbauer, K; Slavc, I; Yang, JW; Strobel, T; Lubec, G. Protein profiles of medulloblastoma cell lines DAOY and D283: identification of tumor-related proteins and principles.. Proteomics. 2003-09, 3 (9): 1781–800 [2019-12-18]. PMID 12973738. doi:10.1002/pmic.200300460. （原始内容存档于2019-12-18）.

[5] Srivastava, VK; Nalbantoglu, J. Flow cytometric characterization of the DAOY medulloblastoma cell line for the cancer stem-like phenotype.. Cytometry. Part A : the journal of the International Society for Analytical Cytology. 2008-10, 73 (10): 940–8 [2019-12-18]. PMID 18773455. doi:10.1002/cyto.a.20633. （原始内容存档于2019-12-18）.

[6] Gingras, D; Gendron, M; Boivin, D; Moghrabi, A; Théorêt, Y; Béliveau, R. Induction of medulloblastoma cell apoptosis by sulforaphane, a dietary anticarcinogen from Brassica vegetables.. Cancer letters. 2004-01-08, 203 (1): 35–43 [2019-12-18]. PMID 14670615. doi:10.1016/j.canlet.2003.08.025. （原始内容存档于2019-12-18）.

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