联苯-4-甲酸

联苯-4-甲酸
识别
CAS号	92-92-2
性质
化学式	C13H10O2
摩尔质量	198.22 g·mol−1
外观	白色固体
熔点	228—230 °C（501—503 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

联苯-4-甲酸是一种有机化合物，化学式为C₁₃H₁₀O₂，它是三种联苯甲酸的同分异构体之一。它可由4-溴苯甲酸和苯硼酸在碳酸钾存在下、钯催化下偶联，生成物酸化后得到；在钯中引入金可以阻止催化剂渗出。^[2]在DMF催化下，它和氯化亚砜^[3]或草酰氯^[4]反应，可以得到联苯-4-甲酰氯。在氟化钠存在下，它和N,N-二乙基二氟硫亚铵氟硼酸盐反应，可以得到联苯-4-甲酰氟。^[5]

参考文献

^ ^1.0 ^1.1 Zhengyin Du, Wanwei Zhou, Fen Wang, Jin-Xian Wang. In situ generation of palladium nanoparticles: ligand-free palladium catalyzed ultrafast Suzuki–Miyaura cross-coupling reaction in aqueous phase at room temperature. Tetrahedron. 2011-07, 67 (26): 4914–4918 [2022-10-19]. doi:10.1016/j.tet.2011.04.093. （原始内容存档于2022-06-19）（英语）.
^ Raghu Nath Dhital, Karan Bobuatong, Masahiro Ehara, Hidehiro Sakurai. Gold/Palladium Alloy for Carbon-Halogen Bond Activation: An Unprecedented Halide Dependence. Chemistry - An Asian Journal. 2015-12, 10 (12): 2669–2676 [2022-10-19]. doi:10.1002/asia.201500722. （原始内容存档于2022-10-19）（英语）.
^ Dongxu Zuo, Qun Wang, Long Liu, Tianzeng Huang, Michal Szostak, Tieqiao Chen. Highly Chemoselective Transamidation of Unactivated Tertiary Amides by Electrophilic N−C(O) Activation by Amide‐to‐Acyl Iodide Re‐routing. Angewandte Chemie International Edition. 2022-06-13, 61 (24) [2022-10-19]. ISSN 1433-7851. doi:10.1002/anie.202202794. （原始内容存档于2022-10-19）（英语）.
^ Md Emdadul Hoque, Mirja Md Mahamudul Hassan, Buddhadeb Chattopadhyay. Remarkably Efficient Iridium Catalysts for Directed C(sp 2 )–H and C(sp 3 )–H Borylation of Diverse Classes of Substrates. Journal of the American Chemical Society. 2021-04-07, 143 (13): 5022–5037 [2022-10-19]. ISSN 0002-7863. doi:10.1021/jacs.0c13415. （原始内容存档于2022-10-19）（英语）.
^ Marie Gonay, Chloé Batisse, Jean-François Paquin. Synthesis of Acyl Fluorides from Carboxylic Acids Using NaF-Assisted Deoxofluorination with XtalFluor-E. The Journal of Organic Chemistry. 2020-08-07, 85 (15): 10253–10260 [2022-10-19]. ISSN 0022-3263. doi:10.1021/acs.joc.0c01377. （原始内容存档于2022-10-21）（英语）.

[Du-1] 1.0 ^1.1 Zhengyin Du, Wanwei Zhou, Fen Wang, Jin-Xian Wang. In situ generation of palladium nanoparticles: ligand-free palladium catalyzed ultrafast Suzuki–Miyaura cross-coupling reaction in aqueous phase at room temperature. Tetrahedron. 2011-07, 67 (26): 4914–4918 [2022-10-19]. doi:10.1016/j.tet.2011.04.093. （原始内容存档于2022-06-19）（英语）.

[2] Raghu Nath Dhital, Karan Bobuatong, Masahiro Ehara, Hidehiro Sakurai. Gold/Palladium Alloy for Carbon-Halogen Bond Activation: An Unprecedented Halide Dependence. Chemistry - An Asian Journal. 2015-12, 10 (12): 2669–2676 [2022-10-19]. doi:10.1002/asia.201500722. （原始内容存档于2022-10-19）（英语）.

[3] Dongxu Zuo, Qun Wang, Long Liu, Tianzeng Huang, Michal Szostak, Tieqiao Chen. Highly Chemoselective Transamidation of Unactivated Tertiary Amides by Electrophilic N−C(O) Activation by Amide‐to‐Acyl Iodide Re‐routing. Angewandte Chemie International Edition. 2022-06-13, 61 (24) [2022-10-19]. ISSN 1433-7851. doi:10.1002/anie.202202794. （原始内容存档于2022-10-19）（英语）.

[4] Md Emdadul Hoque, Mirja Md Mahamudul Hassan, Buddhadeb Chattopadhyay. Remarkably Efficient Iridium Catalysts for Directed C(sp 2 )–H and C(sp 3 )–H Borylation of Diverse Classes of Substrates. Journal of the American Chemical Society. 2021-04-07, 143 (13): 5022–5037 [2022-10-19]. ISSN 0002-7863. doi:10.1021/jacs.0c13415. （原始内容存档于2022-10-19）（英语）.

[5] Marie Gonay, Chloé Batisse, Jean-François Paquin. Synthesis of Acyl Fluorides from Carboxylic Acids Using NaF-Assisted Deoxofluorination with XtalFluor-E. The Journal of Organic Chemistry. 2020-08-07, 85 (15): 10253–10260 [2022-10-19]. ISSN 0022-3263. doi:10.1021/acs.joc.0c01377. （原始内容存档于2022-10-21）（英语）.

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