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丁烷雌酚

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丁烷雌酚
left: (S,S)-butestrol
right: (R,R)-butestrol
临床资料
其他名称Butoestrol; Racemic butestrol; rac-Butestrol; dl-Butestrol; Isobutestrol
药物类别英语Drug classNonsteroidal estrogen
识别信息
  • 4-[(2R,3R)-3-(4-hydroxyphenyl)butan-2-yl]phenol
CAS号5776-76-1  checkY
PubChem CID
ChemSpider
UNII
化学信息
化学式C16H18O2
摩尔质量242.32 g·mol−1
3D模型(JSmol英语JSmol
  • C[C@@H](C1=CC=C(C=C1)O)[C@@H](C)C2=CC=C(C=C2)O
  • InChI=1S/C16H18O2/c1-11(13-3-7-15(17)8-4-13)12(2)14-5-9-16(18)10-6-14/h3-12,17-18H,1-2H3/t11-,12-/m1/s1
  • Key:GDUYFVYTXYOMSJ-VXGBXAGGSA-N

丁烷雌酚(英语:Butestrol)是一种有机化合物,化学式C16H18O2[1],属于人工合成的非甾体雌激素[2],从未上市[3],结构上与乙烯雌酚及其衍生物类似[4]

参考文献

[编辑]
  1. ^ Terenius L. Effect of synthetic oestrogens and analogues on the uptake of oestradiol by the immature mouse uterus and vagina. Acta Pharmacologica et Toxicologica. 1966, 24 (1): 89–100. PMID 6012750. doi:10.1111/j.1600-0773.1966.tb00371.x. 
  2. ^ Martin L, Cox RI, Emmens CW. Further studies on the effects of oestrogens and anti-oestrogens on early pregnancy in mice. Reproduction. 1963, 5 (2): 239–247. ISSN 1470-1626. S2CID 84972967. doi:10.1530/jrf.0.0050239. 
  3. ^ Martin L, Claringbold PJ. The mitogenic action of oestrogens in the vaginal epithelium of the ovariectomized mouse. The Journal of Endocrinology. May 1960, 20 (3): 173–186. PMID 14421704. doi:10.1677/joe.0.0200173. 
  4. ^ Emmens CW, Cox RI, Martin L. The oestrogenic and anti-oestrogenic activity of compounds related to diethylstilboestrol. Acta Endocrinologica. 1964, 45 (4_Suppl): SUPPL90:61–SUPPL90:69. PMID 14117596. doi:10.1530/acta.0.045s061.