转化生长因子-β超家族
外观
Transforming growth factor beta like domain | |||||||||||
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鉴定 | |||||||||||
标志 | TGF_beta | ||||||||||
Pfam | PF00019(旧版) | ||||||||||
InterPro | IPR001839 | ||||||||||
PROSITE | PDOC00223 | ||||||||||
SCOP | 1tfg / SUPFAM | ||||||||||
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转化生长因子-β超家族(transforming growth factor beta superfamily,TGF-β superfamily)是生长因子中的一大家族。分为多个亚家族[2][3][4][5]:
- 转化生长因子-β亚家族,包括:转化生长因子-β1、转化生长因子-β2、转化生长因子-β3
- DVR(decapentaplegic Vg-related)亚家族,包括:
- 激活素与抑制素,如:激活素A、激活素B、抑制素A、抑制素B
- 其他,如:Nodal[6]
参看
[编辑]参考资料
[编辑]- ^ Schlunegger MP, Grütter MG. An unusual feature revealed by the crystal structure at 2.2 A resolution of human transforming growth factor-beta 2. Nature. July 1992, 358 (6385): 430–4. PMID 1641027. doi:10.1038/358430a0.
- ^ Knight, P. G., & Glister, C. (2006). TGF-β superfamily members and ovarian follicle development, Reproduction, 132(2), 191-206. Retrieved Nov 18, 2022, from https://rep.bioscientifica.com/view/journals/rep/132/2/1320191.xml (页面存档备份,存于互联网档案馆)
- ^ Herpin A, Lelong C, Favrel P. Transforming growth factor-beta-related proteins: an ancestral and widespread superfamily of cytokines in metazoans. Dev. Comp. Immunol. May 2004, 28 (5): 461–85. PMID 15062644. doi:10.1016/j.dci.2003.09.007.
- ^ Burt DW. Evolutionary grouping of the transforming growth factor-beta superfamily. Biochem. Biophys. Res. Commun. April 1992, 184 (2): 590–5. PMID 1575734. doi:10.1016/0006-291X(92)90630-4.
- ^ Burt DW, Law AS. Evolution of the transforming growth factor-beta superfamily (PDF). Prog. Growth Factor Res. 1994, 5 (1): 99–118 [2022-11-18]. PMID 8199356. S2CID 41326578. doi:10.1016/0955-2235(94)90020-5. hdl:20.500.11820/50fc2d69-c411-4835-9cd9-36bf4144bae4 . (原始内容存档 (PDF)于2022-11-18).
- ^ Kumar A, Novoselov V, Celeste AJ, Wolfman NM, ten Dijke P, Kuehn MR. Nodal signaling uses activin and transforming growth factor-beta receptor-regulated Smads. J Biol Chem. 2001 Jan 5;276(1):656-61. doi: 10.1074/jbc.M004649200. PMID 11024047.