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老化防護

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老化防護指的是一類以老化和老化相關疾病的肇因為目標、因而可能延長動物壽命的老化防護療法。[1][2][3]一些可能的老化防護藥物包括了褪黑激素[4]肌肽[5]二甲雙胍[6]煙醯胺單核苷酸(nicotinamide mononucleotide,縮寫為NMN)[7][8]δ睡眠肽 (delta sleep-inducing peptide)[9]等等。

參照

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  1. ^ De-novo geroprotector design頁面存檔備份,存於網際網路檔案館), SENS Foundation
  2. ^ Alexey Moskalev, Elizaveta Chernyagina, Anna Kudryavtseva & Mikhail Shaposhnikov. Geroprotectors: A Unified Concept and Screening Approaches. Aging and Disease. 2017, 8 (3): 354–363. PMC 5440114可免費查閱. PMID 28580190. doi:10.14336/AD.2016.1022. 
  3. ^ Alexey Moskalev, Elizaveta Chernyagina, Joao Pedro de Magalhaes & Alex Zhavoronkov. Geroprotectors.org: a new, structured and curated database of current therapeutic interventions in aging and age-related disease. Aging. 2015, 7 (9): 616–628. PMC 4600621可免費查閱. PMID 26342919. doi:10.18632/aging.100799. 
  4. ^ Anisimov, VN; Popovich, IG; Zabezhinski, MA; Anisimov, SV; Vesnushkin, GM; Vinogradova, IA. Melatonin as antioxidant, geroprotector and anticarcinogen. Biochimica et Biophysica Acta (BBA) - Bioenergetics. 2006, 1757 (5–6): 573–89. PMID 16678784. doi:10.1016/j.bbabio.2006.03.012. 
  5. ^ Boldyrev, AA; Stvolinsky, SL; Fedorova, TN; Suslina, ZA. Carnosine as a natural antioxidant and geroprotector: From molecular mechanisms to clinical trials. Rejuvenation Research. 2010, 13 (2–3): 156–8. PMID 20017611. doi:10.1089/rej.2009.0923. 
  6. ^ Bulterijs, S. Metformin As a Geroprotector. Rejuvenation Research. 2011, 14 (5): 469–82. PMID 21882902. S2CID 40645408. doi:10.1089/rej.2011.1153. 
  7. ^ Long-Term Administration of Nicotinamide Mononucleotide Mitigates Age-Associated Physiological Decline in Mice, Cell Metabolism 24, 795–806, December 13, 2016 ª 2016 Elsevier Inc.
  8. ^ 長壽藥”NMN腫瘤能不能喫?不得不說的NMN副作用大全. 互動頭條. [2020-11-30]. (原始內容存檔於2020-12-11) (中文(臺灣)). 
  9. ^ Bondarenko, TI. Mechanism of delta-sleep inducing peptide geroprotective activity. Adv Gerontol. 2011, 24 (1): 80–92. PMID 21809625. 

參見

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外部連結

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