SZ-685C

SZ-685C
英文名	Haloroquinone
別名	1,2,3,4-四氫-1,2,3,5,8-五羥基-6-甲氧基-3-甲基-9,10-蒽醌
識別
CAS號	1222440-09-6
SMILES	O=C1C2=C(O)C(OC)=CC(O)=C2C(=O)C3=C1CC(O)(C)C(O)C3O;
性質
化學式	C16H16O8
摩爾質量	336.29 g·mol−1
	若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。

SZ-685C是一種四氫蒽醌類的有機化合物，化學式為C₁₆H₁₆O₈。它可以通過Akt/FOXO途徑誘導細胞凋亡，被用於抗腫瘤的研究。^[1]它的生物來源是一種海洋真菌Halorosellinia sp.（英語：Halorosellinia），因此該化合物也被稱作「haloroquinone」。^[2]

參考文獻[編輯]

^ Gui'e Xie, Xun Zhu, Qing Li, Minghui Gu, Zhenjian He, Jueheng Wu, Jun Li, Yongcheng Lin, Mengfeng Li, Zhigang She, Jie Yuan. SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway. British Journal of Pharmacology. 2010. 159 (3): 689-697. doi:10.1111/j.1476-5381.2009.00577.x.
^ Chuanpeng Niu, Menghao Cai, Yuanxing Zhang & Xiangshan Zhou. Biosynthetic origin of the carbon skeleton of a novel anti-tumor compound, haloroquinone, from a marine-derived fungus, Halorosellinia sp. Biotechnology Letters, 2012. 34. 2119-2124. doi:10.1007/s10529-012-1019-z.

[1] Gui'e Xie, Xun Zhu, Qing Li, Minghui Gu, Zhenjian He, Jueheng Wu, Jun Li, Yongcheng Lin, Mengfeng Li, Zhigang She, Jie Yuan. SZ-685C, a marine anthraquinone, is a potent inducer of apoptosis with anticancer activity by suppression of the Akt/FOXO pathway. British Journal of Pharmacology. 2010. 159 (3): 689-697. doi:10.1111/j.1476-5381.2009.00577.x.

[2] Chuanpeng Niu, Menghao Cai, Yuanxing Zhang & Xiangshan Zhou. Biosynthetic origin of the carbon skeleton of a novel anti-tumor compound, haloroquinone, from a marine-derived fungus, Halorosellinia sp. Biotechnology Letters, 2012. 34. 2119-2124. doi:10.1007/s10529-012-1019-z.

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