BV2
BV2細胞是最常用的鼠源小膠質細胞細胞系[1]，來自於一周齡的雌性C57BL/6實驗小鼠，通過感染帶有v-raf/v-myc癌基因的J2逆轉錄病毒實現永生化[2]，用於一些神經退行性疾病研究[3]。
參考資料[編輯]
- ^ Henn, A; Lund, S; Hedtjärn, M; Schrattenholz, A; Pörzgen, P; Leist, M. The suitability of BV2 cells as alternative model system for primary microglia cultures or for animal experiments examining brain inflammation.. ALTEX. 2009, 26 (2): 83–94. PMID 19565166. doi:10.14573/altex.2009.2.83.
- ^ Blasi, E; Barluzzi, R; Bocchini, V; Mazzolla, R; Bistoni, F. Immortalization of murine microglial cells by a v-raf/v-myc carrying retrovirus.. Journal of neuroimmunology. 1990-05, 27 (2-3): 229–37. PMID 2110186. doi:10.1016/0165-5728(90)90073-v.
- ^ Crain, JM; Watters, JJ. Estrogen and P2 Purinergic Receptor Systems in Microglia: Therapeutic Targets for Neuroprotection.. The open drug discovery journal. 2010-01-01, 2: 148–167. PMID 21961028. doi:10.2174/1877381801002010148.