蛋白激酶磷酸酶
外观
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![](http://upload.wikimedia.org/wikipedia/commons/thumb/6/60/MKPs_role_in_ERK_regulation.jpg/300px-MKPs_role_in_ERK_regulation.jpg)
蛋白激酶磷酸酶(英语:MAPK phosphatasesare)是一类磷酸酶,涉及MAPK信号传导途径,通过去磷酸化降低MAP激酶信号[1][2]。蛋白激酶信号通路调节发育和稳态的多种特征。[3][4]
![](http://upload.wikimedia.org/wikipedia/commons/thumb/1/1a/The_inactivation_of_MAPKs_by_MKPs.jpg/300px-The_inactivation_of_MAPKs_by_MKPs.jpg)
参考文献
[编辑]- ^ 医学主题词表(MeSH):MAPK+Phosphatases
- ^ Dickinson, Robin J.; Keyse, Stephen M. Diverse physiological functions for dual-specificity MAP kinase phosphatases. J Cell Sci. 15 November 2006, 119 (22): 4607–4615. PMID 17093265. doi:10.1242/jcs.03266
(英语).
- ^ Caunt, Christopher J.; Keyse, Stephen M. Dual-specificity MAP kinase phosphatases (MKPs). FEBS Journal. January 2013, 280 (2): 489–504. PMC 3594966
. PMID 22812510. doi:10.1111/j.1742-4658.2012.08716.x.
- ^ Low, Heng Boon; Zhang, Yongliang. Regulatory Roles of MAPK Phosphatases in Cancer. Immune Network. 2016, 16 (2): 85–98. PMC 4853501
. PMID 27162525. doi:10.4110/in.2016.16.2.85.
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