A20细胞

A20 (亦称ATCC TIB-208) 是于1979年在BALB/c小鼠发现的B细胞淋巴瘤细胞系^[1]，该球状淋巴母细胞（英语：Lymphoblast）的表面光滑且中心部分较暗边缘明显，较常应用于存在免疫缺陷及具有免疫功能的动物模型构建^[2]^[3]，以进行疫苗靶点的选择、研究抗肿瘤免疫机制和筛选药物^[4]^[5]^[6]，由A20细胞所建立的模型的病理学特征与人类弥漫大B细胞淋巴瘤非常类似。

参考资料

^ Kim, KJ; Kanellopoulos-Langevin, C; Merwin, RM; Sachs, DH; Asofsky, R. Establishment and characterization of BALB/c lymphoma lines with B cell properties.. Journal of immunology (Baltimore, Md. : 1950). 1979-02, 122 (2): 549–554 [2019-12-05]. PMID 310843.
^ Küppers, R; Hansmann, ML. The Hodgkin and Reed/Sternberg cell.. The international journal of biochemistry & cell biology. 2005-03, 37 (3): 511–517 [2019-12-05]. PMID 15618006. doi:10.1016/j.biocel.2003.10.025.
^ Yanagisawa, Y; Sato, Y; Asahi-Ozaki, Y; Ito, E; Honma, R; Imai, J; Kanno, T; Kano, M; Akiyama, H; Sata, T; Shinkai-Ouchi, F; Yamakawa, Y; Watanabe, S; Katano, H. Effusion and solid lymphomas have distinctive gene and protein expression profiles in an animal model of primary effusion lymphoma.. The Journal of pathology. 2006-2008, 209 (4): 464–73 [2019-12-05]. PMID 16741895. doi:10.1002/path.2012. 请检查|date=中的日期值 (帮助)
^ Meziane el, K; Bhattacharyya, T; Armstrong, AC; Qian, C; Hawkins, RE; Stern, PL; Dermime, S. Use of adenoviruses encoding CD40L or IL-2 against B cell lymphoma.. International journal of cancer. 2004-10-10, 111 (6): 910–920 [2019-12-05]. PMID 15300803. doi:10.1002/ijc.20332.
^ Siegel, S; Wagner, A; Kabelitz, D; Marget, M; Coggin J, Jr; Barsoum, A; Rohrer, J; Schmitz, N; Zeis, M. Induction of cytotoxic T-cell responses against the oncofetal antigen-immature laminin receptor for the treatment of hematologic malignancies.. Blood. 2003-12-15, 102 (13): 4416–23 [2019-12-05]. PMID 12869512. doi:10.1182/blood-2003-01-0198.
^ Siegel, S; Wagner, A; Schmitz, N; Zeis, M. Induction of antitumour immunity using survivin peptide-pulsed dendritic cells in a murine lymphoma model.. British journal of haematology. 2003-09, 122 (6): 911–4 [2019-12-05]. PMID 12956760. doi:10.1046/j.1365-2141.2003.04535.x.

外部链接

Cellosaurus entry for A20（页面存档备份，存于互联网档案馆）

这是一篇与医学相关的小作品。您可以通过编辑或修订扩充其内容。

[1] Kim, KJ; Kanellopoulos-Langevin, C; Merwin, RM; Sachs, DH; Asofsky, R. Establishment and characterization of BALB/c lymphoma lines with B cell properties.. Journal of immunology (Baltimore, Md. : 1950). 1979-02, 122 (2): 549–554 [2019-12-05]. PMID 310843.

[2] Küppers, R; Hansmann, ML. The Hodgkin and Reed/Sternberg cell.. The international journal of biochemistry & cell biology. 2005-03, 37 (3): 511–517 [2019-12-05]. PMID 15618006. doi:10.1016/j.biocel.2003.10.025.

[3] Yanagisawa, Y; Sato, Y; Asahi-Ozaki, Y; Ito, E; Honma, R; Imai, J; Kanno, T; Kano, M; Akiyama, H; Sata, T; Shinkai-Ouchi, F; Yamakawa, Y; Watanabe, S; Katano, H. Effusion and solid lymphomas have distinctive gene and protein expression profiles in an animal model of primary effusion lymphoma.. The Journal of pathology. 2006-2008, 209 (4): 464–73 [2019-12-05]. PMID 16741895. doi:10.1002/path.2012. 请检查|date=中的日期值 (帮助)

[4] Meziane el, K; Bhattacharyya, T; Armstrong, AC; Qian, C; Hawkins, RE; Stern, PL; Dermime, S. Use of adenoviruses encoding CD40L or IL-2 against B cell lymphoma.. International journal of cancer. 2004-10-10, 111 (6): 910–920 [2019-12-05]. PMID 15300803. doi:10.1002/ijc.20332.

[5] Siegel, S; Wagner, A; Kabelitz, D; Marget, M; Coggin J, Jr; Barsoum, A; Rohrer, J; Schmitz, N; Zeis, M. Induction of cytotoxic T-cell responses against the oncofetal antigen-immature laminin receptor for the treatment of hematologic malignancies.. Blood. 2003-12-15, 102 (13): 4416–23 [2019-12-05]. PMID 12869512. doi:10.1182/blood-2003-01-0198.

[6] Siegel, S; Wagner, A; Schmitz, N; Zeis, M. Induction of antitumour immunity using survivin peptide-pulsed dendritic cells in a murine lymphoma model.. British journal of haematology. 2003-09, 122 (6): 911–4 [2019-12-05]. PMID 12956760. doi:10.1046/j.1365-2141.2003.04535.x.

[1]

[2]

[3]

[4]

[5]

[6]