讨论:酰基载体蛋白
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未翻译内容
[编辑]未翻译内容如下：--Flame 欢迎泡茶 2011年5月7日 (六) 00:19 (UTC)
首先，fulfils two demands in these biosynthetic pathways. First, the intermediates remain covalently linked to the synthases (or synthetases) in an energy-rich linkage. Second, the flexibility and length of phosphopantetheine chain (approximately 2 nm) allows the covalently-tethered intermediates to have access to spatially-distinct enzyme-active sites. This increases the effective molarity of the intermediate and allows an assemblyline-like process.
The ACPs are small negatively-charged α-helical bundle proteins with a high degree of structural and amino acid similarity. The structures of a number of acyl carrier proteins have been solved using various 蛋白质核磁共振光谱与X光结晶学的技术。
The ACPs are related in structure and mechanism to the peptidyl carrier proteins (PCP) from nonribosomal peptide synthases.
- 翻译完毕——Shakiestone (留言) 2011年9月13日 (二) 10:21 (UTC)