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齒孔醇

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齒孔醇
IUPAC名
(3S,5R,10S,13R,14R,17R)-4,4,10,13,14-pentamethyl-17-[(2R)-6-methyl-5-methylideneheptan-2-yl]-2,3,5,6,7,11,12,15,16,17-decahydro-1H-cyclopenta[a]phenanthren-3-ol
系統名
4,4,14alpha-trimethyl-5alpha-ergosta-8,24(28)-dien-3beta-ol
識別
CAS號 6890-88-6
PubChem 9803310
ChemSpider 7979070
SMILES
 
  • C[C@H](CCC(=C)C(C)C)[C@H]1CC[C@@]2([C@@]1(CCC3=C2CC[C@@H]4[C@@]3(CC[C@@H](C4(C)C)O)C)C)C
InChI
 
  • 1S/C31H52O/c1-20(2)21(3)10-11-22(4)23-14-18-31(9)25-12-13-26-28(5,6)27(32)16-17-29(26,7)24(25)15-19-30(23,31)8/h20,22-23,26-27,32H,3,10-19H2,1-2,4-9H3/t22-,23-,26+,27+,29-,30-,31+/m1/s1
InChIKey XJLZCPIILZRCPS-ANMPWZFDSA-N
ChEBI 70315
性質
化學式 C31H52O
摩爾質量 440.74 g·mol−1
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

齒孔醇(英語:Eburicol,又叫鈍葉二烯醇,Obtusifoldienol,或24-亞甲基-24,25-二氫羊毛甾醇,24-Methylene-24,25-dihydrolanosterol)是化學式為C31H52O的天然真菌甾醇,可被酵母細胞色素P450甾醇14α-去甲基酶ERG11脫甲基化[1]

參考文獻

[編輯]
  1. ^ Aoyama, Y; Yoshida, Y. Different substrate specificities of lanosterol 14a-demethylase (P-45014DM) of Saccharomyces cerevisiae and rat liver for 24-methylene-24,25-dihydrolanosterol and 24,25-dihydrolanosterol.. Biochemical and biophysical research communications. 15 August 1991, 178 (3): 1064–71. PMID 1872829. doi:10.1016/0006-291x(91)91000-3.