2-溴-5-硝基苯甲醛

2-溴-5-硝基苯甲醛
识别
CAS号	84459-32-5
SMILES	O=Cc1cc([N+](=O)[O-])ccc1Br;
性质
化学式	C7H4BrNO3
摩尔质量	230.02 g·mol⁻¹
熔点	105—107 °C（378—380 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

2-溴-5-硝基苯甲醛是一种有机化合物，化学式为C₇H₄BrNO₃。它可由2-溴-5-硝基苯甲醇和吡啶氯铬酸盐在二氯甲烷中的氧化反应制得；^[2]混酸在0 °C硝化2-溴苯甲醛也可以得到产物。^[3]在碳酸钠和四(三苯基膦)钯的存在下，它可以和苯硼酸发生偶联反应，得到4-硝基联苯-2-甲醛。^[4]

参考文献[编辑]

^ Emmanuelle Dubost, Christine Fossey, Thomas Cailly, Sylvain Rault, Frederic Fabis. Selective ortho -Bromination of Substituted Benzaldoximes Using Pd-Catalyzed C–H Activation: Application to the Synthesis of Substituted 2-Bromobenzaldehydes. The Journal of Organic Chemistry. 2011-08-05, 76 (15): 6414–6420 [2021-05-19]. ISSN 0022-3263. doi:10.1021/jo200853j （英语）.
^ Takeo Kawabata, Changsheng Jiang, Kazuhiro Hayashi, Kazunori Tsubaki, Tomoyuki Yoshimura, Swapan Majumdar, Takahiro Sasamori, Norihiro Tokitoh. Axially Chiral Binaphthyl Surrogates with an Inner N−H−N Hydrogen Bond. Journal of the American Chemical Society. 2009-01-14, 131 (1): 54–55 [2021-05-19]. ISSN 0002-7863. doi:10.1021/ja808213r. （原始内容存档于2021-02-27）（英语）.
^ Tsuyoshi Yamada, Kwihwan Park, Takumu Tachikawa, Akiko Fujii, Matthias Rudolph, A. Stephen K. Hashmi, Hironao Sajiki. Gold-Catalyzed Cyclization of 2-Alkynylaldehyde Cyclic Acetals via Hydride Shift for the Synthesis of Indenone Derivatives. Organic Letters. 2020-03-06, 22 (5): 1883–1888 [2021-05-19]. ISSN 1523-7060. doi:10.1021/acs.orglett.0c00221 （英语）.
^ Dongyang Wang, Jing Zhao, Jun Chen, Qing Xu, Huan Li. Intramolecular Arylative Ring Opening of Donor‐Acceptor Cyclopropanes in the Presence of Triflic Acid: Synthesis of 9 H ‐Fluorenes and 9,10‐Dihydrophenanthrenes. Asian Journal of Organic Chemistry. 2019-11, 8 (11): 2032–2036 [2021-05-19]. ISSN 2193-5807. doi:10.1002/ajoc.201900523 （英语）.

[1] Emmanuelle Dubost, Christine Fossey, Thomas Cailly, Sylvain Rault, Frederic Fabis. Selective ortho -Bromination of Substituted Benzaldoximes Using Pd-Catalyzed C–H Activation: Application to the Synthesis of Substituted 2-Bromobenzaldehydes. The Journal of Organic Chemistry. 2011-08-05, 76 (15): 6414–6420 [2021-05-19]. ISSN 0022-3263. doi:10.1021/jo200853j （英语）.

[2] Takeo Kawabata, Changsheng Jiang, Kazuhiro Hayashi, Kazunori Tsubaki, Tomoyuki Yoshimura, Swapan Majumdar, Takahiro Sasamori, Norihiro Tokitoh. Axially Chiral Binaphthyl Surrogates with an Inner N−H−N Hydrogen Bond. Journal of the American Chemical Society. 2009-01-14, 131 (1): 54–55 [2021-05-19]. ISSN 0002-7863. doi:10.1021/ja808213r. （原始内容存档于2021-02-27）（英语）.

[3] Tsuyoshi Yamada, Kwihwan Park, Takumu Tachikawa, Akiko Fujii, Matthias Rudolph, A. Stephen K. Hashmi, Hironao Sajiki. Gold-Catalyzed Cyclization of 2-Alkynylaldehyde Cyclic Acetals via Hydride Shift for the Synthesis of Indenone Derivatives. Organic Letters. 2020-03-06, 22 (5): 1883–1888 [2021-05-19]. ISSN 1523-7060. doi:10.1021/acs.orglett.0c00221 （英语）.

[4] Dongyang Wang, Jing Zhao, Jun Chen, Qing Xu, Huan Li. Intramolecular Arylative Ring Opening of Donor‐Acceptor Cyclopropanes in the Presence of Triflic Acid: Synthesis of 9 H ‐Fluorenes and 9,10‐Dihydrophenanthrenes. Asian Journal of Organic Chemistry. 2019-11, 8 (11): 2032–2036 [2021-05-19]. ISSN 2193-5807. doi:10.1002/ajoc.201900523 （英语）.

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