蛋白质合成GTP酶

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Protein-synthesizing GTPase
蛋白质合成相关GTP酶
识别码
EC编号 3.6.5.3
数据库
IntEnz IntEnz浏览
BRENDA英语BRENDA BRENDA入口
ExPASy英语ExPASy NiceZyme浏览
KEGG KEGG入口
MetaCyc英语MetaCyc 代谢路径
PRIAM英语PRIAM_enzyme-specific_profiles 概述
PDB RCSB PDB PDBe PDBsum

蛋白质合成GTP酶英语:Protein-synthesizing GTPasesEC 3.6.5.3)是指许多参与mRNA翻译为蛋白质的起始因子(IF)、延伸因子(EF)和释放因子(RF),其系统名为GTP phosphohydrolase (mRNA-translation-assisting)[1][2][3][4][5],包括翻译的起始因子IF-2延伸因子EF-Tu

参考文献[编辑]

  1. ^ Kurzchalia, T.V., Bommer, U.A., Babkina, G.T. and Karpova, G.G. GTP interacts with the γ-subunit of eukaryotic initiation factor EIF-2. FEBS Lett. 1984, 175 (2): 313–316. PMID 6566615. 
  2. ^ Kisselev, L.L. and Frolova, L.Yu. Termination of translation in eukaryotes. Biochem. Cell Biol. 1995, 73 (11-12): 1079–1086. PMID 8722024. 
  3. ^ Rodnina, M.V., Savelsberg, A., Katunin, V.I. and Wintermeyer, W. Hydrolysis of GTP by elongation factor G drives tRNA movement on the ribosome. Nature. 1997, 385 (6611): 37–41. PMID 8985244. doi:10.1038/385037a0. 
  4. ^ Freistroffer, D.V., Pavlov, M.Y., MacDougall, J., Buckingham, R.H. and Ehrenberg, M. Release factor RF3 in E. coli accelerates the dissociation of release factors RF1 and RF2 from the ribosome in a GTP-dependent manner. EMBO J. 1997, 16: 4126–4133. PMID 9233821. doi:10.1093/emboj/16.13.4126. 
  5. ^ Krab, I.M. and Parmeggiani, A. EF-Tu, a GTPase odyssey. Biochim. Biophys. Acta. 1998, 1443 (1-2): 1–22. PMID 9838020. 

外部链接[编辑]