血綠素

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Chlorocruorin.

血綠素Chlorocruorin)是一種存在於多種環節動物(特別是多個多毛綱物種,例如龍介蟲科血液血漿裡的帶氧蛋白[1][2][3],負責為身體組織攜帶氧氣。這種血綠素與氧氣結合的親和力較大多數的血紅蛋白為低,但與一氧化碳結合的親和力,是人血內的血紅素的570倍[4]

血綠素是一種(雙色英语dichromatism)化合物,其顏色隨含氧量而變: 脫氧時呈綠色,但帶氧時呈紅色;在濃度低的溶液呈綠色、濃度高時變淺紅色[5][6][7]

血綠素是一個巨大分子,但不存在於紅血球內,而是自由地在血漿內漂浮[8][9]其結構跟無脊椎動物血紅蛋白英语erythrocruorin非常相像;而無脊椎動物血紅蛋白的結構又跟肌紅蛋白(myoglobin)只有幾個subunits的差異。它本身由多組16-17kDa的類肌紅蛋白單元排列,形成一個有超過一百個單元的巨型複雜構造,蛋白間有互連,總重量超過3600kDa。The only significant difference between chlorocruorin and erythrocruorin is that chlorocruorin carries an abnormal heme group structure[8]

參考文獻[编辑]

  1. ^ H. Munro Fox. The Blood Circulation of Animals Possessing Chlorocruorin. Proceedings of the Royal Society B. 1933-04-01, 112 (779): 479–495. JSTOR 81599. doi:10.1098/rspb.1938.0042. 
  2. ^ R. F. Ewer, H. Munro Fox. On the Function of Chlorocruorin. Proceedings of the Royal Society B. 1940-08-09, 129 (855): 137–153. JSTOR 82389. doi:10.1098/rspb.1940.0033. 
  3. ^ D.W. Ewer. The blood systems of Sabella and Spirographis. Quarterly Journal of Microscopical Science. 1941, 82 (s2): 587–619 [2010-05-01]. 
  4. ^ Cowles, David. Serpula vermicularis Linnaeus, 1767. Invertebrates of the Salish Sea. Rosario Beach Marine Laboratory at Walla Walla University. 2006 [2011-10-31]. 
  5. ^ H. Munro Fox. Chlorocruorin: A Pigment Allied to Haemoglobin. Proceedings of the Royal Society B. 1926-02-01, 99 (696): 199–220. JSTOR 81088. doi:10.1098/rspb.1926.0008. 
  6. ^ H. Munro Fox. The Oxygen Affinity of Chlorocruorin. Proceedings of the Royal Society B. 1 September 1932, 111 (772): 356–363. JSTOR 81716. doi:10.1098/rspb.1932.0060. 
  7. ^ H. Munro Fox. On Chlorocruorin and Haemoglobin. Proceedings of the Royal Society B. 19 October 1949, 136 (884): 378–388. JSTOR 82565. doi:10.1098/rspb.1949.0031. 
  8. ^ 8.0 8.1 Pallavicini A, Negrisolo E, Barbato R; 等. The primary structure of globin and linker chains from the chlorocruorin of the polychaete Sabella spallanzanii. J. Biol. Chem. July 2001, 276 (28): 26384–90. PMID 11294828. doi:10.1074/jbc.M006939200. 
  9. ^ Lamy JN, Green BN, Toulmond A, Wall JS, Weber RE, Vinogradov SN. Giant Hexagonal Bilayer Hemoglobins. Chem Rev. 1996-12-19, 96 (8): 3113–3124. PMID 11848854. doi:10.1021/cr9600058 (英语). 

外部連結[编辑]