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感染力

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感染力(infectivity)為流行病學名詞,指病原體感染宿主的能力。病原體的感染力一般與其毒力正相關[1]。常用的感染力量化單位為ID50,即達到50%感染率所需的病原數量,其數值越低代表病原的感染力越高[2],不同病源的ID50差異很大,如痢疾志賀氏桿菌英语Shigella dysenteriae的ID50為10,霍亂弧菌的ID50則為106至1011[3]

參見

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  • 致病性(Pathogenicity):指病原體感染後造成臨床可見症狀的能力[4]

參考文獻

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  1. ^ Stewart, AD; Logsdon, JM; Kelley, SE. An empirical study of the evolution of virulence under both horizontal and vertical transmission. Evolution. April 2005, 59 (4): 730–739. PMID 15926685. doi:10.1554/03-330. 
  2. ^ Wessels, Michael R.; Gama, João Alves; Abby, Sophie S.; Vieira-Silva, Sara; Dionisio, Francisco; Rocha, Eduardo P. C. Immune Subversion and Quorum-Sensing Shape the Variation in Infectious Dose among Bacterial Pathogens. PLoS Pathogens. 2012, 8 (2): e1002503. ISSN 1553-7374. doi:10.1371/journal.ppat.1002503. 
  3. ^ van Seventer, Jean Maguire; Hochberg, Natasha S. Principles of Infectious Diseases: Transmission, Diagnosis, Prevention, and Control: 22–39. 2017. doi:10.1016/B978-0-12-803678-5.00516-6. 
  4. ^ Lesson 1: Introduction to Epidemiology / Section 9: Natural History and Spectrum of Disease. CDC. 2012 [2021-03-18]. (原始内容存档于2021-03-18).