4,5,6,7-四氯-2-三氟甲基苯並咪唑
| TTFB | |
|---|---|
| |
| 識別 | |
| CAS號 | 2338-29-6 
|
| PubChem | 75357 |
| ChemSpider | 67893 |
| SMILES |
|
| ChEBI | 1744 |
| KEGG | C11322 |
| 性質 | |
| 化學式 | C8HCl4F3N2 |
| 摩爾質量 | 323.91 g·mol−1 |
| 外觀 | 白色固體[1] |
| 熔點 | 274-276 °C[1] |
| 危險性 | |
| 致死量或濃度： | |
LD50（中位劑量）
|
23 mg/kg（小鼠，腹膜）[2] |
| 若非註明，所有數據均出自標準狀態（25 ℃，100 kPa）下。 | |
4,5,6,7-四氯-2-三氟甲基苯並咪唑是一種有機化合物，化學式為C8HCl4F3N2。它可由2-三氟甲基苯並咪唑和王水反應製得。[1]它和碘甲烷在碳酸鉀存在下於丙酮中回流，可以得到4,5,6,7-四氯-1-甲基-2-三氟甲基苯並咪唑。[3]
參考文獻
[編輯]- ^ 1.0 1.1 1.2 Laudy, Agnieszka E.; Moo‐Puc, Rosa; Cedillo‐Rivera, Roberto; Kazimierczuk, Zygmunt; Orzeszko, Andrzej. Synthesis and Antimicrobial Activities of New Polyhalogenated Benzimidazoles. Journal of Heterocyclic Chemistry (Wiley). 2012, 49 (5): 1059–1065. ISSN 0022-152X. doi:10.1002/jhet.936.
- ^ Ilivicky, J; Casida, JE. Uncoupling action of 2,4-dinitrophenols, 2-trifluoromethylbenzimidazoles and certain other pesticide chemicals upon mitochondria from different sources and its relation to toxicity.. Biochemical Pharmacology. June 1969, 18 (6): 1389–401. PMID 5799112. doi:10.1016/0006-2952(69)90252-4.
- ^ Kawazoe, Kentaro; Yoshioka, Kotaro. Fluoroalkylating agents, preparation of fluoroalkylated compounds using them, benzimidazolium salts for them, and their use. 2015. WO2015199109.