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4,5,6,7-四氯-2-三氟甲基苯並咪唑

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識別
CAS號 2338-29-6  checkY
PubChem 75357
ChemSpider 67893
SMILES
 
  • C12=C(C(=C(C(=C1Cl)Cl)Cl)Cl)N=C(N2)C(F)(F)F
ChEBI 1744
KEGG C11322
性質
化學式 C8HCl4F3N2
摩爾質量 323.91 g·mol−1
外觀 白色固體[1]
熔點 274-276 °C[1]
危險性
致死量或濃度:
LD50中位劑量
23 mg/kg(小鼠,腹膜)[2]
若非註明,所有數據均出自標準狀態(25 ℃,100 kPa)下。

4,5,6,7-四氯-2-三氟甲基苯並咪唑是一種有機化合物,化學式為C8HCl4F3N2。它可由2-三氟甲基苯並咪唑和王水反應製得。[1]它和碘甲烷碳酸鉀存在下於丙酮中回流,可以得到4,5,6,7-四氯-1-甲基-2-三氟甲基苯並咪唑。[3]

參考文獻

[編輯]
  1. ^ 1.0 1.1 1.2 Laudy, Agnieszka E.; Moo‐Puc, Rosa; Cedillo‐Rivera, Roberto; Kazimierczuk, Zygmunt; Orzeszko, Andrzej. Synthesis and Antimicrobial Activities of New Polyhalogenated Benzimidazoles. Journal of Heterocyclic Chemistry (Wiley). 2012, 49 (5): 1059–1065. ISSN 0022-152X. doi:10.1002/jhet.936. 
  2. ^ Ilivicky, J; Casida, JE. Uncoupling action of 2,4-dinitrophenols, 2-trifluoromethylbenzimidazoles and certain other pesticide chemicals upon mitochondria from different sources and its relation to toxicity.. Biochemical Pharmacology. June 1969, 18 (6): 1389–401. PMID 5799112. doi:10.1016/0006-2952(69)90252-4. 
  3. ^ Kawazoe, Kentaro; Yoshioka, Kotaro. Fluoroalkylating agents, preparation of fluoroalkylated compounds using them, benzimidazolium salts for them, and their use. 2015. WO2015199109.